Journal of Pharmaceutical Sciences

Cover image for Journal of Pharmaceutical Sciences

Special Issue: Dedicated to Michael J. Pikal

September 2009

Volume 98, Issue 9

Pages 2869–3498

  1. Commentaries

    1. Top of page
    2. Commentaries
    3. Reviews
    4. Research Articles
    5. Note
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  2. Reviews

    1. Top of page
    2. Commentaries
    3. Reviews
    4. Research Articles
    5. Note
    1. You have free access to this content
      Mechanisms of protein stabilization in the solid state (pages 2886–2908)

      Liuquan (Lucy) Chang and Michael J. Pikal

      Article first published online: 30 JUN 2009 | DOI: 10.1002/jps.21825

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      Protein aggregation: Pathways, induction factors and analysis (pages 2909–2934)

      Hanns-Christian Mahler, Wolfgang Friess, Ulla Grauschopf and Sylvia Kiese

      Article first published online: 29 SEP 2008 | DOI: 10.1002/jps.21566

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  3. Research Articles

    1. Top of page
    2. Commentaries
    3. Reviews
    4. Research Articles
    5. Note
    1. Biotechnology

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      Mixing properties of lyophilized protein systems: A spectroscopic and calorimetric study (pages 2954–2969)

      Derrick S. Katayama, John F. Carpenter, Kevin P. Menard, Mark Cornell Manning and Theodore W. Randolph

      Article first published online: 11 JUL 2008 | DOI: 10.1002/jps.21467

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      Stability of a trivalent recombinant protein vaccine formulation against botulinum neurotoxin during storage in aqueous solution (pages 2970–2993)

      Christina Vessely, Tia Estey, Theodore W. Randolph, Ian Henderson, Julianne Cooper, Rajiv Nayar, LaToya Jones Braun and John F. Carpenter

      Article first published online: 4 AUG 2008 | DOI: 10.1002/jps.21498

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      Evaluation of chemical degradation of a trivalent recombinant protein vaccine against botulinum neurotoxin by LysC peptide mapping and MALDI-TOF mass spectrometry (pages 2994–3012)

      Tia Estey, Christina Vessely, Theodore W. Randolph, Ian Henderson, LaToya Jones Braun, Rajiv Nayar and John F. Carpenter

      Article first published online: 9 SEP 2008 | DOI: 10.1002/jps.21543

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      Elucidation of two major aggregation pathways in an IgG2 antibody (pages 3013–3030)

      Nicholas Van Buren, Douglas Rehder, Himanshu Gadgil, Masazumi Matsumura and Jaby Jacob

      Article first published online: 4 AUG 2008 | DOI: 10.1002/jps.21514

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      Conformational implications of an inversed pH-dependent antibody aggregation (pages 3031–3042)

      Natalie Perico, Judith Purtell, Thomas M. Dillon and Margaret S. Ricci

      Article first published online: 19 SEP 2008 | DOI: 10.1002/jps.21539

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      Liquid high concentration IgG1 antibody formulations by precipitation (pages 3043–3057)

      Susanne Matheus, Wolfgang Friess, Daniel Schwartz and Hanns-Christian Mahler

      Article first published online: 29 SEP 2008 | DOI: 10.1002/jps.21526

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      Quantitation of protein particles in parenteral solutions using micro-flow imaging (pages 3058–3071)

      Chi-Ting Huang, Deepak Sharma, Peter Oma and Rajesh Krishnamurthy

      Article first published online: 20 OCT 2008 | DOI: 10.1002/jps.21575

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      Temperature scanning FTIR analysis of secondary structures of proteins embedded in amorphous sugar matrix (pages 3088–3098)

      Koreyoshi Imamura, Ken-ichi Ohyama, Toru Yokoyama, Yoshinobu Maruyama and Nakanishi Kazuhiro

      Article first published online: 13 NOV 2008 | DOI: 10.1002/jps.21568

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      Characterization of the photodegradation of a human IgG1 monoclonal antibody formulated as a high-concentration liquid dosage form (pages 3117–3130)

      Pei Qi, David B. Volkin, Hui Zhao, Michael L. Nedved, Robert Hughes, Ryan Bass, Sun C. Yi, Mark E. Panek, Dana Wang, Paul DalMonte and Michael D. Bond

      Article first published online: 13 NOV 2008 | DOI: 10.1002/jps.21617

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      Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution (pages 3167–3181)

      Renuka Thirumangalathu, Sampathkumar Krishnan, Margaret Speed Ricci, David N. Brems, Theodore W. Randolph and John F. Carpenter

      Article first published online: 9 APR 2009 | DOI: 10.1002/jps.21719

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      Light-induced aggregation of type I soluble tumor necrosis factor receptor (pages 3182–3199)

      Shouvik Roy, Bruce D. Mason, Christian S. Schöneich, John F. Carpenter, Thomas C. Boone and Bruce A. Kerwin

      Article first published online: 21 APR 2009 | DOI: 10.1002/jps.21750

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      Physical and biophysical effects of polysorbate 20 and 80 on darbepoetin alfa (pages 3200–3217)

      Songpon Deechongkit, Jie Wen, Linda O. Narhi, Yijia Jiang, Sungae S. Park, Justin Kim and Bruce A. Kerwin

      Article first published online: 22 APR 2009 | DOI: 10.1002/jps.21740

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      Monoclonal antibody interactions with micro- and nanoparticles: Adsorption, aggregation, and accelerated stress studies (pages 3218–3238)

      Jared S. Bee, David Chiu, Suzanne Sawicki, Jennifer L. Stevenson, Koustuv Chatterjee, Erwin Freund, John F. Carpenter and Theodore W. Randolph

      Article first published online: 2 JUN 2009 | DOI: 10.1002/jps.21768

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      Immunogenicity of aggregates of recombinant human growth hormone in mouse models (pages 3247–3264)

      Amber Haynes Fradkin, John F. Carpenter and Theodore W. Randolph

      Article first published online: 30 JUN 2009 | DOI: 10.1002/jps.21834

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      Analysis of insulin allostery in solution and solid state with FTIR (pages 3265–3277)

      Morten Jonas Maltesen, Simon Bjerregaard, Lars Hovgaard, Svend Havelund and Marco van de Weert

      Article first published online: 1 APR 2009 | DOI: 10.1002/jps.21736

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      Precipitation of a monoclonal antibody by soluble tungsten (pages 3290–3301)

      Jared S. Bee, Stephanie A. Nelson, Erwin Freund, John F. Carpenter and Theodore W. Randolph

      Article first published online: 19 FEB 2009 | DOI: 10.1002/jps.21707

    24. Drug Discovery Interface

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      Extreme sensitivity of botulinum neurotoxin domains towards mild agitation (pages 3302–3311)

      Stephen I. Toth, Leonard A. Smith and S. Ashraf Ahmed

      Article first published online: 18 FEB 2009 | DOI: 10.1002/jps.21676

    25. Pharmaceutics, Preformulation and Drug Delivery

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      Structural stability of hepatitis C virus envelope glycoprotein E1: Effect of pH and dissociative detergents (pages 3340–3357)

      Feng He, Sangeeta B. Joshi, Fons Bosman, Marijke Verhaeghe and C. Russell Middaugh

      Article first published online: 12 DEC 2008 | DOI: 10.1002/jps.21657

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    35. Pharmaceutical Technology

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      In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools (pages 3430–3446)

      T.R.M. De Beer, P. Vercruysse, A. Burggraeve, T. Quinten, J. Ouyang, X. Zhang, C. Vervaet, J.P. Remon and W.R.G. Baeyens

      Article first published online: 7 JAN 2009 | DOI: 10.1002/jps.21633

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      Amorphous drug–PVP dispersions: Application of theoretical, thermal and spectroscopic analytical techniques to the study of a molecule with intermolecular bonds in both the crystalline and pure amorphous state (pages 3456–3468)

      Michael Tobyn, Jonathan Brown, Andrew B. Dennis, Michael Fakes, Qi Gao, John Gamble, Yaroslav Z. Khimyak, Gary McGeorge, Chhaya Patel, Wayne Sinclair, Peter Timmins and Shawn Yin

      Article first published online: 14 JUL 2009 | DOI: 10.1002/jps.21738

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      Computational analysis of fluid dynamics in pharmaceutical freeze-drying (pages 3483–3494)

      Alina A. Alexeenko, Arnab Ganguly and Steven L. Nail

      Article first published online: 30 JUN 2009 | DOI: 10.1002/jps.21862

  4. Note

    1. Top of page
    2. Commentaries
    3. Reviews
    4. Research Articles
    5. Note
    1. You have free access to this content

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