Research Article

Resonance Raman spectroscopic studies of [Ru(phen)2qdppz]2+ and its interactions with calf thymus DNA

  1. B. Abraham1,
  2. C. V. Sastri2,
  3. B. G. Maiya2,
  4. S. Umapathy1,†,*

Article first published online: 14 NOV 2003

DOI: 10.1002/jrs.1072

Issue

Journal of Raman Spectroscopy

Journal of Raman Spectroscopy

Volume 35, Issue 1, pages 13–18, January 2004

Additional Information

How to Cite

Abraham, B., Sastri, C. V., Maiya, B. G. and Umapathy, S. (2004), Resonance Raman spectroscopic studies of [Ru(phen)2qdppz]2+ and its interactions with calf thymus DNA. J. Raman Spectrosc., 35: 13–18. doi: 10.1002/jrs.1072

Author Information

  1. 1

    Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore-560012, India

  2. 2

    School of Chemistry, University of Hyderabad, Gachibowli-500046, India

  1. †

    Swarna Jayanthi Fellow.

*Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore-560012, India.

  1. †

    Swarna Jayanthi Fellow.

Publication History

  1. Issue published online: 2 JAN 2004
  2. Article first published online: 14 NOV 2003
  3. Manuscript Accepted: 7 JUL 2003
  4. Manuscript Received: 22 APR 2003

Funded by

  • Department of Science and Technology.
  • Council of Scientific and Industrial Research (CSIR).

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Keywords:

  • Resonance Raman;
  • [Ru(phen)2qdppz]2+;
  • calf thymus DNA;
  • intercalation

Abstract

Resonance Raman (RR) spectroscopy was employed to study the metal to ligand charge transfer (MLCT) and intraligand transition (IL) state of the [Ru(phen)2qdppz]2+ complex, where phen = 1, 10-phenanthroline and qdppz = naphtho[2,3-a]dipyrido[3,2-h:2′,3′-f]phenazine-5,18-dione. The vibrational bands were assigned based on the data available for [Ru(phen)2dppz]2+ (dppz = dipyrido[3,2-a:2′,3′-c]phenazine), [Ru(dppz)3]2+ and [Ru(phen)3]2+. The tail end of the MLCT band is inferred to be the Ru → qdppz localized transition based on vibrational intensity analysis. On intercalation with DNA, the modes assigned to qdppz decrease in intensity owing to ππ stacking interactions with the DNA bases. RR data show that the above complex binds to DNA through intercalation via the qdppz moiety. Copyright © 2003 John Wiley & Sons, Ltd.

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