Identification and characterization of pharmaceuticals using Raman and surface-enhanced Raman scattering
Article first published online: 5 MAY 2004
Copyright © 2004 John Wiley & Sons, Ltd.
Journal of Raman Spectroscopy
Special Issue: Pharmaceutical Applications of Raman Spectroscopy
Volume 35, Issue 5, pages 338–346, May 2004
How to Cite
Cîntǎ Pînzaru, S., Pavel, I., Leopold, N. and Kiefer, W. (2004), Identification and characterization of pharmaceuticals using Raman and surface-enhanced Raman scattering. J. Raman Spectrosc., 35: 338–346. doi: 10.1002/jrs.1153
- Issue published online: 5 MAY 2004
- Article first published online: 5 MAY 2004
- Manuscript Accepted: 17 DEC 2003
- Manuscript Received: 6 OCT 2003
- Deutsche Forschungsgemeinschaft. Grant Number: SFB 630, Teilprojekt C1
- Fonds der Chemischen Industrie
Many recent papers reflect ongoing research and development concerning pharmaceutical applications of Raman techniques. This short review highlights different Raman techniques (dispersive, Fourier transform, resonance Raman, SERS, SERRS, FT-SERS) employed in pharmaceutical investigations. Several Raman applications such as fundamental structural investigations, quantitative analysis, drug–excipient interaction, formulation, limit of detection, pH-dependent pharmaceutical species, adsorption geometry at a given surface and functional groups involved in adsorption for several widely used pharmaceutical compounds are presented. Copyright © 2004 John Wiley & Sons, Ltd.