SERS detection of proteins on micropatterned protein-mediated sandwich substrates (pages 1492–1496)
Weidong Ruan, Wei Ji, Xiangxin Xue, Yang Cui, Lei Chen, Tieli Zhou, Li Niu, Xiao Li, Junhu Zhang and Bing Zhao
Article first published online: 23 FEB 2011 | DOI: 10.1002/jrs.2892
Surface-enhanced Raman scattering (SERS) technique was employed as a platform to detect micropatterned protein-mediated Au/Ag sandwich substrates. The resulting spectra showed high sensitivity and good resolution. The results indicate that SERS is a powerful tool in the detection of proteins and has great potential application in protein chips.