• paste electrode;
  • DNA;
  • carbon nanotube;
  • voltammetry;
  • vitamin E


BACKGROUND: A voltammetric study of vitamin E (DL-α-tocopherol) detection using square wave stripping and cyclic voltammetry is discussed in this paper. The working sensor was made by mixing carbon nanotube powder with DNA (double-stranded calf thymus DNA) and mineral oil. In this electrode, the anodic peak was obtained for − 0.6 V in a 0.1 mol L−1 phosphate electrolyte solution.

RESULTS: Under optimized stripping conditions, analytical linear working ranges of 0.5–4.0 µg L−1 and 40.0–160.0 µg L−1 were obtained. The RSD precision was pegged at 0.105% with seven points using an 80 µg L−1 spike. The detection limit (S/N) was found to be 0.056 µg L−1 (1.30 × 10−10 mol L−1).

CONCLUSION: The developed method was found to be applicable to quality control analysis in the food, pharmaceutical and other manufacturing sectors. Copyright © 2008 Society of Chemical Industry