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Keywords:

  • optical imaging;
  • fluorescence;
  • sentinel lymph node;
  • angiography;
  • tumour detection

Abstract

Optical imaging using near-infrared (NIR) fluorescence provides new prospects for general and oncologic surgery. ICG is currently utilised in NIR fluorescence cancer-related surgery for three indications: sentinel lymph node (SLN) mapping, intraoperative identification of solid tumours, and angiography during reconstructive surgery. Therefore, understanding its advantages and limitations is of significant importance. Although non-targeted and non-conjugatable, ICG appears to be laying the foundation for more widespread use of NIR fluorescence-guided surgery. J. Surg. Oncol. 2011; 104:323–332. © 2011 Wiley-Liss, Inc.