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Keywords:

  • melanoma in-transit metastases;
  • electrochemotherapy;
  • intralesional immunotherapy

Abstract

Regional relapse of melanoma may occur as satellite or in-transit metastases proximal to the primary tumor in the direction of the lymph flow. The management of in-transit metastases is challenging because the efficacy of treatment is largely dictated by the biological behavior of the patient's melanoma. This review examines local treatment modalities. J. Surg. Oncol. 2011; 104:391–396. © 2011 Wiley-Liss, Inc.