Systemic treatment of metastatic melanoma: New approaches
Version of Record online: 19 AUG 2011
Copyright © 2011 Wiley-Liss, Inc.
Journal of Surgical Oncology
Special Issue: Seminars in Surgical Oncology: Melanoma
Volume 104, Issue 4, pages 425–429, 15 September 2011
How to Cite
Hamid, O., Boasberg, P. D., Rosenthal, K. and O'Day, S. J. (2011), Systemic treatment of metastatic melanoma: New approaches. J. Surg. Oncol., 104: 425–429. doi: 10.1002/jso.22034
- Issue online: 17 AUG 2011
- Version of Record online: 19 AUG 2011
- Manuscript Accepted: 24 JUN 2011
- Manuscript Received: 15 SEP 2010
- metastatic melanoma;
The field of melanoma therapeutics has experienced a dramatic paradigm shift over the last 12 months through recent discoveries of novel therapeutics targeting known oncogenes and immunotherapeutic antibodies. In this article, we review these findings and provide a framework to understand these discoveries, their significance in melanoma therapy, and role in clinical care. As this understanding grows, enduring therapeutic success may be achieved through tailored use of molecular markers and immunotherapies in sequential or combinatorial methods. J. Surg. Oncol. 2011; 104:425–429. © 2011 Wiley-Liss, Inc.