B lymphocytes as effector cells in the immunotherapy of cancer
Version of Record online: 6 SEP 2011
Copyright © 2011 Wiley Periodicals, Inc.
Journal of Surgical Oncology
Volume 105, Issue 4, pages 431–435, 15 March 2012
How to Cite
Namm, J. P., Li, Q., Lao, X., Lubman, D. M., He, J., Liu, Y., Zhu, J., Wei, S. and Chang, A. E. (2012), B lymphocytes as effector cells in the immunotherapy of cancer. J. Surg. Oncol., 105: 431–435. doi: 10.1002/jso.22093
- Issue online: 6 FEB 2012
- Version of Record online: 6 SEP 2011
- Manuscript Accepted: 17 AUG 2011
- Manuscript Received: 15 JUL 2011
- Gillson Longenbaugh Foundation
- B cells;
- adoptive immunotherapy;
- tumor antigen
Over the years, the role of B cells in the host immune response to malignancy has been overshadowed by our focus on T cells. Nevertheless, B cells play important roles as antigen-presenting cells and in the production of antibodies. Furthermore, B cells can function as effector cells that mediate tumor destruction on their own. This review will highlight the various functions of B cells that are involved in the host response to tumor. J. Surg. Oncol. 2012;105:431–435. © 2011 Wiley Periodicals, Inc.