Long-term survival with thorotrast cervical granuloma
Version of Record online: 19 JUL 2006
Copyright © 1978 Wiley-Liss, Inc., A Wiley Company
Journal of Surgical Oncology
Volume 10, Issue 2, pages 171–177, 1978
How to Cite
Lung, R. J., Harding, R. L., Herceg, S. J., Schantz, J. C. and Miller, S. H. (1978), Long-term survival with thorotrast cervical granuloma. J. Surg. Oncol., 10: 171–177. doi: 10.1002/jso.2930100209
- Issue online: 19 JUL 2006
- Version of Record online: 19 JUL 2006
- thorium dioxide;
- long-term survival
Thorium dioxide, a radioactive contrast material, was commonly used for cerebral angiography prior to recognition of its radiation hazard. Extravasation of the material into the extravascular tissue in the neck results in granuloma formation, thorotrastoma, long-term morbidity, and an increased incidence of benign and malignant tumors.
We report our experience with the management of 2 patients who underwent cerebral angiography with thorotrast more than 25 years ago. Aggressive surgical excision of involved tissue is warranted to ameliorate symptoms and diminish the risk of malignancy.