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Article

Chemical and hematological screening in patients with malignant and non-malignant conditions

  1. Dr. Yeu-Tsu N. Lee MD†*,
  2. Hubert J. Van Peenen MD,
  3. Francis R. Watson PhD

Article first published online: 20 JUL 2006

DOI: 10.1002/jso.2930150108

Issue

Journal of Surgical Oncology

Journal of Surgical Oncology

Volume 15, Issue 1, pages 43–51, September 1980

Additional Information

How to Cite

Lee, Y.-T. N., Van Peenen, H. J. and Watson, F. R. (1980), Chemical and hematological screening in patients with malignant and non-malignant conditions. J. Surg. Oncol., 15: 43–51. doi: 10.1002/jso.2930150108

Author Information

  1. Departments of Surgery and Biomathematics, Ellis Fischel State Cancer Hospital and Cancer Research Center, and the Missouri Regional Medical Program, Columbia, Missouri, 65201

  1. †

    Department of Surgery, School of Medicine, University of Southern California, Los Angeles, CA 90033

*Department of Surgery, School of Medicine, University of Southern California, Los Angeles, CA 90033

Publication History

  1. Issue published online: 20 JUL 2006
  2. Article first published online: 20 JUL 2006

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Keywords:

  • chemical screening;
  • hematological screening

Abstract

The value of multiphasic automated laboratory tests in differentiating stages of malignancy and in detecting recurrence of cancer was studied. Chemical SMA-12 tests (including calcium, phosphate, glucose, BUN, uric acid, cholesterol, total protein, albumin, total bilirubin, alkaline phosphatase (AP), lactic dehydrogenase (LDH) and SGOT) and hematological SMA-4 tests (including hematocrit, hemoglobin, WBC and RBC counts) were performed in 1,578 patients. Baseline data obtained from 582 patients with benign, and 996 patients with malignant, lesions were subdivided according to age, sex, primary site, and extent of cancer. With advancing stages of cancer, there was a significant increase of AP and LDH, but decrease of albumin and hemoglobin. Among patients who had sequential tests, there was a significant decrease of uric acid and LDH with control of cancer, and increase of AP with development of distant dissemination.

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