Clinicopathologic study of patients with Borrmann type iv gastric carcinoma
Article first published online: 19 JUL 2006
Copyright © 1995 Wiley-Liss, Inc., A Wiley Company
Journal of Surgical Oncology
Volume 58, Issue 2, pages 112–117, February 1995
How to Cite
Kitamura, K., Beppu, R., Anai, H., Ikejiri, K., Yakabe, S., Saku, M. and Sugimachi, K. (1995), Clinicopathologic study of patients with Borrmann type iv gastric carcinoma. J. Surg. Oncol., 58: 112–117. doi: 10.1002/jso.2930580208
- Issue published online: 19 JUL 2006
- Article first published online: 19 JUL 2006
- Manuscript Accepted: 5 OCT 1994
- Borrmann type IV;
- gastric carcinoma;
- linitis plastica;
- scirrhous type carcinoma;
Between 1979 and 1993, 665 Japanese patients with advanced gastric cancer underwent surgery at our hospital. These patients were divided into two groups, consisting of 102 patients with Borrmann type IV carcinoma, and the remaining 563 patients with all other types of gastric carcinoma, which were then compared clinicopathologically.
In the patients with Borrmann type IV carcinoma, 77.4% of the lesions demonstrated poorly differentiated adenocarcinoma, and 99 patients were classified as Stage III or IV. The resection rate was 87.2% (89/102) with only 39 curative operations despite the fact that 70 total gastrectomies were performed. The incidence of peritoneal dissemination (29.4%) and serosal invasion (97.0%) was significantly higher in these patients. Microscopic lymph node metastasis was positive in 86.5%. The 5-year survival rate was 23.4% in the patients with a curative operation and 5.0% in those with a noncurative operation (p < 0.01). Peritoneal dissemination was most frequently noted in the recurrence patterns.
We conclude that early detection and a curative operation are both essential to improve the prognosis of patients with Borrmann type IV gastric cancer. The addition of a potent postoperative chemotherapy regimen is also recommended. © 1995 Wiley-Liss, Inc.