Size exclusion chromatography – A blessing and a curse of science and technology of synthetic polymers

Authors

  • Dušan Berek

    Corresponding author
    1. Laboratory of Liquid Chromatography, Polymer Institute, Slovak Academy of Sciences, Bratislava, Slovakia
    • Laboratory of Liquid Chromatography, Polymer Institute, Slovak Academy of Sciences, Dúbravská cesta 9, 84236 Bratislava, Slovakia Fax:+421-2-54775923
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Abstract

Size exclusion chromatography, SEC is one of the most popular methods for the separation of different kinds of macromolecules. This critical review gives concise information about macromolecules and their behavior in solution, basic understanding about principles, instrumentation, and application possibilities of SEC, and more in detail discusses drawbacks and pitfalls of the method with the emphasis on synthetic polymers. Selected practical advices are included to help enhance the quality of SEC results.

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