Flow-through immobilized enzyme reactors based on monoliths: II. Kinetics study and application

Authors

  • Evgenia G. Vlakh,

    1. Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
    2. Faculty of Chemistry, Saint-Petersburg State University, St. Petersburg, Russia
    Search for more papers by this author
  • Tatiana B. Tennikova

    Corresponding author
    1. Faculty of Chemistry, Saint-Petersburg State University, St. Petersburg, Russia
    • Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
    Search for more papers by this author

  • This paper is included in the virtual special issue Monoliths available at the Journal of Separation Science website.

Correspondence: Professor Tatiana B. Tennikova, Russian Academy of Sciences, Institute of Macromolecular Compounds, Bolshoy pr. 31, 199004, St. Petersburg, Russia

E-mail: tennikova@mail.ru

Fax: +7812-323-68-69

Abstract

In the last decade, the application of monolithic materials has rapidly expanded to the realization of flow-through bioconversion processes. Up to these days, different classes of enzymes such as hydrolases, lyases, and oxidoreductases have been immobilized on organic, inorganic, or hybrid monolithic materials to prepare the effective flow-through enzymes reactors for application in proteomics, biotechnology, pharmaceutics, organic synthesis, and biosensoring. Current review describes the results of kinetic study and specialties of flow-through immobilized enzyme reactors based on the existing monolithic materials.

Ancillary