This work was supported by INSERM, Assistance Publique des Hôpitaux de Paris (AP-HP), AgenceNationale pour la Recherche (ANR-ProjectManage-BP), Fondation pour la Recherche sur le Cerveau (FRC) and RTRS Santé Mentale (Fondation FondaMental).We thank E. Abadie, C. Bulach, B. Cochet, M. Fabbro, and M. J. Pereira Gomes for their assistance. We thank patients and controls for their participation.
Preferential association between childhood emotional abuse and bipolar disorder†
Article first published online: 25 MAY 2010
Copyright © 2010 International Society for Traumatic Stress Studies
Journal of Traumatic Stress
Volume 23, Issue 3, pages 376–383, June 2010
How to Cite
Etain, B., Mathieu, F., Henry, C., Raust, A., Roy, I., Germain, A., Leboyer, M. and Bellivier, F. (2010), Preferential association between childhood emotional abuse and bipolar disorder. J. Traum. Stress, 23: 376–383. doi: 10.1002/jts.20532
- Issue published online: 16 JUN 2010
- Article first published online: 25 MAY 2010
Childhood trauma has been suggested to be involved in the susceptibility to bipolar disorder. However, case-control studies are lacking, and the preferential implication and the dose-effect of different trauma subtypes remain poorly investigated. Two hundred six bipolar patients and 94 controls completed the Childhood Trauma Questionnaire (CTQ; Bernstein et al., 1994). The CTQ total score was higher for bipolar patients than for controls. The presence of multiple trauma was significantly more frequent in bipolar patients than in controls (63% vs. 33%). Multiple logistic regression suggested that only emotional abuse was associated with bipolar disorder with a suggestive dose-effect. Clinical practice should include systematic assessment of childhood trauma among bipolar patients with a particular focus on emotional abuse.