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Although co-occurring posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) is associated with greater distress, impairment, and health care utilization than PTSD alone, the magnitude of this problem is uncertain. This meta-analysis aimed to estimate the mean prevalence of current MDD co-occurrence among individuals with PTSD and examine potential moderating variables (U.S. nationality, gender, trauma type, military service, referral type) that may influence the rate of PTSD and MDD co-occurrence. Meta-analytic findings (k = 57 studies; N = 6,670 participants) revealed that 52%, 95% confidence interval [48, 56], of individuals with current PTSD had co-occurring MDD. When outliers were removed, military samples and interpersonal traumas demonstrated higher rates of MDD among individuals with PTSD than civilian samples and natural disasters, respectively. U.S. nationality, gender, and referral type did not significantly account for differences in co-occurrence rates. This high co-occurrence rate accentuates the importance of routinely assessing MDD among individuals with PTSD and continuing research into the association between these disorders.

Traditional and Simplified Chinese Abstracts by AsianSTSS

標題:創傷後壓力症和抑鬱症的共病性的元分析

撮要:雖然同時患上創傷後壓力症(PTSD)和抑鬱症(MDD)帶來更多困擾、損害和使用醫療服務,但問題幅度未明。本元分析希望在PTSD患者中評估現在MDD共病性的平均流行率,和檢視影響PTSD和MDD共病率的可能緩解變量(包括美國籍、性別、創傷類別、兵役和轉介類別)。元分析結論(k=57個研究,N=6,670人)顯示52%現有PTSD患者同時患上MDD(95%CI=[48,56])。異常值去除後,PTSD患者中軍人比平民有更高MDD比率,而人際創傷亦較自然災害有更高MDD比率。美國籍、性別和轉介類別都未能解釋共病比率的差異。高共病比率教我們在評估PTSD患者時必須常規評核MDD,和對這些疾病的相連性多作研究。

标题:创伤后压力症和抑郁症的共病性的元分析

撮要:虽然同时患上创伤后压力症(PTSD)和抑郁症(MDD)带来更多困扰、损害和使用医疗服务,但问题幅度未明。本元分析希望在PTSD患者中评估现在MDD共病性的平均流行率,和检视影响PTSD和MDD共病率的可能缓解变量(包括美国籍、性别、创伤类别、兵役和转介类别)。元分析结论(k=57个研究,N=6,670人)显示52%现有PTSD患者同时患上MDD(95%CI=[48,56])。异常值去除后,PTSD患者中军人比平民有更高MDD比率,而人际创伤亦较自然灾害有更高MDD比率。美国籍、性别和转介类别都未能解释共病比率的差异。高共病比率教我们在评估PTSD患者时必须常规评核MDD,和对这些疾病的相连性多作研究。