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Cortisol and PTSD Symptoms Among Male and Female High-Exposure 9/11 Survivors

Authors


  • Sharon Dekel was sponsored by Narsad (Dr. Dylan Tauber) and George A. Bonanno received grants BCS-0202772 and BCS-0337643 from the National Science Foundation.

Abstract

Only a few studies have examined cortisol response to trauma-related stressors in relation to posttraumatic stress disorder (PTSD). We followed a sample of high-exposure survivors of the attacks on September 11, 2001 (9/11; 32 men and 29 women) and examined their cortisol response after recalling the escape from the attack, 7 and 18 months post-9/11. PTSD symptoms and saliva cortisol levels were assessed before and after trauma recollection. Hierarchical regression analyses revealed that PTSD symptoms and male sex predicted increased cortisol response following recollections. For men, elevated cortisol was associated with greater severity of reexperiencing symptoms (p < .001) and lower severity of avoidance symptoms (p < .001). For women, recall-induced cortisol was minimal and unrelated to PTSD symptoms (p = .164 and p = .331, respectively). These findings suggest that augmented cortisol response to trauma-related stressors may be evident in men reporting symptoms of PTSD. Thus, as cortisol abnormalities related to PTSD symptoms appear sex-specific, future research on mechanisms of sex differences in response to trauma is warranted.

Traditional and Simplified Chinese Abstracts by AsianSTSS

標題 : ⌈911⌋恐怖襲擊中有嚴重經歷的男女倖存者皮質醇水平和PTSD症狀的關係

撮要 :只有少量現存研究檢視PTSD中創傷相關壓力源引致皮質醇反應。我們追蹤一批有⌈911⌋恐怖襲擊嚴重經歷的倖存者(共32名男士和29名女士)樣本,並檢視在襲擊後7個月及18個月後他們的皮質醇對重溫襲擊後逃脫的反應。創傷回憶前後則評估PTSD症狀和唾液皮質醇水平。層次回歸分析顯示PTSD症狀和男性均預測創傷回憶後上升皮質醇反應。男性而言, 皮質醇上升則和較嚴重的經歷症狀(p<.001)及較少逃避症狀(p<.001)有關連。女性而言,回憶引發的皮質醇是少量的,亦與PTSD症狀無關(分別是p=.164和p=.331) 。結果指出在投訴PTSD症狀的男性中創傷相關壓力源可能加強皮質醇反應。所以PTSD症狀有關皮質醇異常是性別特定的,而創傷引起性別差異的機制必須加強研究。

标题 : ⌈911⌋恐怖袭击中有严重经历的男女幸存者皮质醇水平和PTSD症状的关系

撮要 :只有少量现存研究检视PTSD中创伤相关压力源引致皮质醇反应。我们追踪一批有⌈911⌋恐怖袭击严重经历的幸存者(共32名男士和29名女士)样本,并检视在袭击后7个月及18个月后他们的皮质醇对重温袭击后逃脱的反应。创伤回忆前后则评估PTSD症状和唾液皮质醇水平。层次回归分析显示PTSD症状和男性均预测创伤回忆后上升皮质醇反应。男性而言, 皮质醇上升则和较严重的经历症状(p<.001)及较少逃避症状(p<.001)有关连。女性而言,回忆引发的皮质醇是少量的,亦与PTSD症状无关(分别是p=.164和p=.331) 。结果指出在投诉PTSD症状的男性中创伤相关压力源可能加强皮质醇反应。所以PTSD症状有关皮质醇异常是性别特定的,而创伤引起性别差异的机制必须加强研究。

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