Head and Neck

Parotid mucosa-associated lymphoid tissue lymphoma regression after Helicobacter pylori eradication

  1. Hiroshi Iwai MD, PhD1,*,
  2. Naoto Nakamichi MD, PhD2,
  3. Kaori Nakae MD1,
  4. Masaya Konishi MD, PhD1,
  5. Muneo Inaba PhD3,
  6. Shoichi Hoshino MD3,
  7. Susumu Baba MD, PhD1,
  8. Ryuichi Amakawa MD, PhD2

Article first published online: 5 JUN 2009

DOI: 10.1002/lary.20258

Issue

The Laryngoscope

The Laryngoscope

Volume 119, Issue 8, pages 1491–1494, August 2009

Additional Information

How to Cite

Iwai, H., Nakamichi, N., Nakae, K., Konishi, M., Inaba, M., Hoshino, S., Baba, S. and Amakawa, R. (2009), Parotid mucosa-associated lymphoid tissue lymphoma regression after Helicobacter pylori eradication. The Laryngoscope, 119: 1491–1494. doi: 10.1002/lary.20258

Author Information

  1. 1

    Department of Otolaryngology, Takii Hospital, Kansai Medical University, Osaka, Japan

  2. 2

    First Department of Internal Medicine, Takii Hospital, Kansai Medical University, Osaka, Japan

  3. 3

    First Department of Pathology, Takii Hospital, Kansai Medical University, Osaka, Japan

*Department of Otolaryngology, Kansai Medical University, 10-15 Fumizonocho, Moriguchi, Osaka 570-8507, Japan

Publication History

  1. Issue published online: 21 JUL 2009
  2. Article first published online: 5 JUN 2009
  3. Manuscript Accepted: 17 FEB 2009
  4. Manuscript Revised: 11 FEB 2009
  5. Manuscript Received: 6 NOV 2008

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Keywords:

  • Sjögren's syndrome;
  • serum sIL-2R antigen;
  • extragastric MALT lymphoma;
  • Helicobacter pylori

Abstract

A 60-year-old woman with Sjögren's syndrome showed recurrence of parotid mucosa-associated lymphoid tissue (MALT) lymphoma with a simultaneous increase of serum sIL-2R antigen levels 10 years after surgical treatment. Helicobacter pylori infection had been detected in the stomach since the beginning of the lymphoma. Although H. pylori was not detected in the recurrent parotid lymphoma, antibiotic therapy contributed not only to successful eradication of gastric H. pylori but also to disappearance of the recurrent lymphoma. Further studies on the mechanisms of occurrence of extragastric MALT lymphomas are needed to establish the treatment of extragastric MALT lymphomas. Laryngoscope, 2009

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