A new pH catheter for laryngopharyngeal reflux: Normal values
Article first published online: 5 JUN 2009
Copyright © 2009 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 119, Issue 8, pages 1639–1643, August 2009
How to Cite
Sun, G., Muddana, S., Slaughter, J. C., Casey, S., Hill, E., Farrokhi, F., Garrett, C. G. and Vaezi, M. F. (2009), A new pH catheter for laryngopharyngeal reflux: Normal values. The Laryngoscope, 119: 1639–1643. doi: 10.1002/lary.20282
- Issue published online: 21 JUL 2009
- Article first published online: 5 JUN 2009
- Manuscript Accepted: 23 FEB 2009
- Manuscript Revised: 19 FEB 2009
- Manuscript Received: 2 JAN 2009
- Laryngopharyngeal reflux;
Laryngopharyngeal reflux (LPR) represents a challenging field. Therapeutic studies of proton pump inhibitors in LPR have shown mixed results. The Restech pH catheter (Respiratory Technology Corp., San Diego, CA) is a minimally invasive device for detection of oropharyngeal acid reflux. The aim of this study was to provide normative data using this device in both distal esophagus and oropharynx.
Prospective observational study.
Normal volunteers were recruited to undergo pH monitoring. A custom made longer catheter was used to assess distal esophageal pH. Oropharyngeal pH catheter was placed at the level of uvula. The distribution of % time was summarized using the 5th, 25th, 50th (median), 75th, and 95th quantiles for pH < 6, pH < 5, and pH < 4 for both upright and supine positions.
A total of 20 normal, healthy volunteers underwent pH monitoring for 14 to 24 hours (median 20.5 hours). The 95th percentile for % total time pH < 4, pH < 5, pH < 6 for the distal esophageal pH catheter were 4.52%, 10.91%, and 42.99%, respectively. For the oropharynx pH probe, the 95th percentile for % total time pH < 4, pH < 5, and pH < 6 were 0.02%, 2.33%, and 21.41% respectively. The 95th percentile for number of reflux events for total pH < 4, pH < 5, and pH < 6 were 1.3, 8.1, and 128.0, respectively.
Oropharyngeal acid reflux is an infrequent occurrence in healthy volunteers without LPR. The normative data for Restech pH catheter may now be compared to those with suspected LPR. Laryngoscope, 2009