Tonsillectomy in post-transplant lymphoproliferative disease in children
Article first published online: 3 FEB 2010
Copyright © 2010 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 120, Issue 3, pages 608–611, March 2010
How to Cite
Sturm-O'Brien, A. K., Hicks, M. J., Giannoni, C. M., Sulek, M. and Friedman, E. M. (2010), Tonsillectomy in post-transplant lymphoproliferative disease in children. The Laryngoscope, 120: 608–611. doi: 10.1002/lary.20799
- Issue published online: 16 FEB 2010
- Article first published online: 3 FEB 2010
- Manuscript Accepted: 4 NOV 2009
- post-transplant lymphoproliferative disease;
- adenotonsillar hypertrophy;
- liver transplant
To review the role of tonsillectomy in diagnosis and management of post-transplant lymphoproliferative disorder (PTLD).
Case series using a retrospective chart review.
A retrospective review of post-transplant lymphoproliferative disease at a tertiary academic medical center from January 2004 to April 2008. Data extracted includes patients' gender, age at transplantation, year of transplantation and tonsillectomy, type of transplant, presenting symptoms, type of immunosuppression, and outcome.
Six out of 25 (24%) patients who underwent tonsillectomy were found to have PTLD. The patient's characteristics, gender, age at transplantation, year of transplantation and tonsillectomy, type of transplant, presenting symptoms, type of immunosuppression, and outcomes are discussed.
In our series, tonsillar hypertrophy, male gender, young age at transplantation, and liver transplantation were associated with higher rates of PTLD. Given the devastating nature of PTLD, early detection with tonsillectomy and institution of treatment is critical. Laryngoscope, 2010