Presented at the 27th Politzer Society Meeting, London, United Kingdom, September 3–5, 2009.
Version of Record online: 7 SEP 2010
Copyright © 2010 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 120, Issue 11, pages 2270–2276, November 2010
How to Cite
Kim, Y. H., Chang, M. Y., Jung, H. H., Park, Y. S., Lee, S. H., Lee, J. H., Oh, S.-H., Chang, S. O. and Koo, J.-W. (2010), Prognosis of ramsay hunt syndrome presenting as cranial polyneuropathy. The Laryngoscope, 120: 2270–2276. doi: 10.1002/lary.21108
This study was supported by a clinical research grant provided by the Seoul National University, Boramae Medical Center. The authors have no other funding, financial relationships, or conflicts of interest to disclose.
- Issue online: 22 OCT 2010
- Version of Record online: 7 SEP 2010
- Manuscript Accepted: 12 MAY 2010
- Ramsay Hunt syndrome;
- cranial polyneuropathy;
Ramsay Hunt syndrome is known to be accompanied with cranial polyneuropathy very occasionally. We reviewed our experience to analyze the clinical manifestations and prognosis of these cases.
Eleven patients with Ramsay Hunt syndrome presenting as cranial polyneuropathy between 1999 and 2009 were included in this study retrospectively. All patients were treated with systemic steroids and antiviral agents. Assessment of recovery from facial nerve palsy (FNP) using the House-Brackmann (HB) grading system was performed, and the follow-up period was 4 to 28 months.
The patient numbers for the initial degree of FNP were five for HB grade II, one for grade III, two for grade IV, and three for grade V. The cochleovestibular nerve was involved in 10 cases, and hearing loss was observed in nine patients. Other involved cranial nerves were IX in seven cases, X in five cases, V in three cases, and III/XII in one case each. Antiviral agents and steroids were administered within 3 days after the onset of symptoms for about 1 to 2 weeks in most cases. After the treatment the degree of FNP improved to HB grade I or II in nine of 11 patients (81.8%). Symptoms of other cranial nerves also improved in most patients, whereas recovery for hearing loss showed poor results.
Ramsay Hunt syndrome associated with cranial polyneuropathy has a good prognosis for FNP and other cranial nerve palsies with a combination therapy of antiviral agents and steroids, but not for recovery of hearing loss. Laryngoscope, 2010