A rare case of laryngeal dystonia associated with neurosyphilis: Response to botulinum toxin injection1

Authors

  • Ki-Hong Kevin Ho MD,

    Corresponding author
    1. Department of Otolaryngology, University of Texas Medical Branch, Galveston, Texas, U.S.A.
    • Department of Otolaryngology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-0521
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    • The authors have no funding, financial relationships, or conflicts of interest to disclose

  • Christopher C. Wright MD,

    1. Department of Internal Medicine, Baylor College of Medicine, Houston, Texas, U.S.A.
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  • Michael P. Underbrink MD, MBA

    1. Department of Otolaryngology, University of Texas Medical Branch, Galveston, Texas, U.S.A.
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  • 1

    Presented at the 112th Annual Triological Society Meeting, Phoenix, Arizona, U.S.A., May 28–30, 2009.

Abstract

We report a unique case of laryngeal dystonia in a 43-year-old male with neurosyphilis who underwent successful treatment with botulinum toxin injection. To date there have been no reports of laryngeal dystonia associated with neurosyphilis. The patient initially presented with strained and stuttering voice despite systemic penicillin therapy. After 2 months of speech therapy with limited relief, the patient received botulinum toxin injection to each thyroarytenoid muscle. Postinjection videostroboscopy showed marked improvement of voice quality. Laryngoscope, 2011

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