Laryngology

The use of adalimumab for cricoarytenoid arthritis in ankylosing spondylitis—an effective therapy†‡

  1. Gauthier Desuter MD, MSc1,*,
  2. Thierry Duprez MD2,
  3. Caroline Huart MD,
  4. Quentin Gardiner MD1,3,
  5. Gust Verbruggen MD, PhD4

Article first published online: 13 JAN 2011

DOI: 10.1002/lary.21343

Issue

The Laryngoscope

The Laryngoscope

Volume 121, Issue 2, pages 335–338, February 2011

Additional Information

How to Cite

Desuter, G., Duprez, T., Huart, C., Gardiner, Q. and Verbruggen, G. (2011), The use of adalimumab for cricoarytenoid arthritis in ankylosing spondylitis—an effective therapy. The Laryngoscope, 121: 335–338. doi: 10.1002/lary.21343

Author Information

  1. 1

    Otolaryngology, Head and Neck Surgery Department, Voice and Swallowing clinic, Cliniques Universitaires Saint-Luc, Universite Catholique de Louvain, Brussels, Belgium

  2. 2

    Radiology Department, Cliniques Universitaires Saint-Luc, Universite Catholique de Louvain, Brussels, Belgium

  3. 3

    Otolaryngology, Head and Neck Surgery Department, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom

  4. 4

    Rheumatology Department, Ghent University Hospital, Ghent University, Ghent, Belgium

*Otolaryngology Head and Neck Surgery Department, Voice and Swallowing Clinic, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10 avenue Hippocrate, 1200 Brussels, Belgium

  1. †

    The authors have no financial disclosures for this article. All authors deny any financial or material support for their work. Likewise, all authors deny any financial interest in any company or entity concerned by this work.

  2. ‡

    The authors have no conflicts of interest to declare.

Publication History

  1. Issue published online: 26 JAN 2011
  2. Article first published online: 13 JAN 2011
  3. Manuscript Accepted: 27 AUG 2010
  4. Manuscript Received: 24 AUG 2010

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (760K)

Keywords:

  • Laryngology

Abstract

This report describes cartilaginous regeneration in a cricoarytenoid joint affected by spondyloarthropathy using tumor necrosis factor-alpha (TNF-α) blockade, monitored by magnetic resonance (MR) and computed tomography (CT) imaging. This case is interesting for several reasons. It is only the eighth case of destructive ankylosing spondylitis-related cricoarytenoid arthritis published in the English language literature. It describes, for the first time, full recovery of vocal cord mobility following TNF-α blockade. It is also the first case to be published with MR imaging demonstrating regeneration of the cricoarytenoid cartilage following treatment. This case represents a landmark in the treatment of patients presenting with destructive arthritis involving the cricoarytenoid joint.

View Full Article (HTML) Get PDF (760K)