Otology

Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: A Case Report†

  1. Walter Di Nardo MD, PhD1,
  2. Paola Cattani MD, PhD2,
  3. Alessandro Scorpecci MD1,*,
  4. Sara Giannantonio MD1,
  5. Sara D'Onghia MD2,
  6. Giovanni Fadda MD, PhD2,
  7. Gaetano Paludetti MD, PhD1

Article first published online: 8 FEB 2011

DOI: 10.1002/lary.21447

Issue

The Laryngoscope

The Laryngoscope

Volume 121, Issue 4, pages 828–830, April 2011

Additional Information

How to Cite

Di Nardo, W., Cattani, P., Scorpecci, A., Giannantonio, S., D'Onghia, S., Fadda, G. and Paludetti, G. (2011), Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: A Case Report. The Laryngoscope, 121: 828–830. doi: 10.1002/lary.21447

Author Information

  1. 1

    Department of Otorhinolaryngology , Catholic University of the Sacred Heart, Rome, Italy

  2. 2

    the Institute of Microbiology , Catholic University of the Sacred Heart, Rome, Italy

*Institute of Otorhinolaryngology, Catholic University of the Sacred Heart, “A. Gemelli” University Hospital, Largo Gemelli, 8, 00168 Rome, Italy

  1. †

    The authors have no funding, financial relationships, or conflicts of interest to disclose.

Publication History

  1. Issue published online: 23 MAR 2011
  2. Article first published online: 8 FEB 2011
  3. Manuscript Accepted: 9 NOV 2010
  4. Manuscript Revised: 5 NOV 2010
  5. Manuscript Received: 5 OCT 2010

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Keywords:

  • Cochlear implants;
  • acquired cytomegalovirus infection;
  • real-time polymerase chain reaction;
  • GJB2 mutation

Abstract

In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection. Laryngoscope, 2011

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