This study was presented at the 2010 American Head and Neck Society Annual Meeting, Las Vegas, NV.
Version of Record online: 7 JUL 2011
Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 121, Issue 9, pages 2001–2003, September 2011
How to Cite
Zevallos, J. P., Jain, K. S., Roberts, D., El-Naggar, A., Hanna, E. Y. and Kupferman, M. E. (2011), Sinonasal malignancies in children: A 10-year, single-institutional review. The Laryngoscope, 121: 2001–2003. doi: 10.1002/lary.21793
There is no grant or external financial support.
The authors have no financial disclosures for this article.
The authors have no conflicts of interest to disclose.
- Issue online: 24 AUG 2011
- Version of Record online: 7 JUL 2011
- Manuscript Accepted: 7 DEC 2010
- Manuscript Received: 19 AUG 2010
- Pediatric sinonasal malignancies;
- Level of Evidence: 2b.
Sinonasal malignancies in children are rare, histologically diverse tumors that present diagnostic and management challenges. The purpose of this study is to review the experience of a single cancer center in the management of pediatric sinonasal malignancies.
Retrospective chart review.
Forty-four patients were identified. The median age was 12 years (range: 2–17), 54% were female, and the maxillary sinus was the most common primary site. Facial swelling and pain were the most common presenting complaints. Thirty-four patients (76%) in this series had paranasal sinus sarcomas, three patients had esthesioneuroblastomas, and eight patients had carcinomas. The 5-year overall survival, disease-specific survival, and recurrence rate for the entire group was 71%, 81%, and 43%, respectively.
Pediatric sinonasal malignancies are rare, locally aggressive tumors associated with nonspecific signs and symptoms. Multimodality treatment can result in 5-year overall and disease-specific survival rates of over 70%. A multidisciplinary team approach is essential to optimize outcomes and limit the morbidity of treatment.