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Effect of hyperdry amniotic membrane patches attached over the bony surface of mastoid cavities in canal wall down tympanoplasty

Authors

  • Hideo Shojaku MD, PhD,

    Corresponding author
    1. Department of Otolaryngology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan
    • Department of Otolaryngology, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan
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  • Hiromasa Takakura MD, PhD,

    1. Department of Otolaryngology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan
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  • Motonori Okabe PhD,

    1. Department of Otolaryngology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan
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  • Michiro Fujisaka MD, PhD,

    1. Department of Otolaryngology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan
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  • Yukio Watanabe MD, PhD,

    1. Department of Regenerative Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
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  • Toshio Nikaido PhD

    1. Department of Regenerative Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
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  • This research was supported by the Japan Society for the Promotion of Science (JSPS), Kakenhi, Grant-in-Aid for Scientific Research (20390430).

  • The authors have no conflicts of interest to disclose.

Abstract

Objectives:

To overcome the lack of the autografts in revision ear surgery, the usefulness of human amniotic membrane (AM) patches as a dressing substitute for fascia grafts of the temporal muscle (temporalis fascia graft) was investigated in canal wall down tympanoplasty.

Study Design:

Retrospective chart review.

Methods:

In 11 ears of 11 patients, the AM was attached over the bony surface of the mastoid cavity (AM group). In 11 ears of nine patients, the temporalis fascia graft was attached over the bony surface of the mastoid cavity (fascia group). The times for graft epithelization were compared in both groups.

Results:

In both groups, complete epithelization of the mastoid cavity took place in all patients. The time of epithelization in the AM group was 32 days, whereas in the fascia group it was 45 days. Complete epithelization of the AM graft was significantly faster than the fascia graft (P < .05).

Conclusions:

Hyperdry AM might be a new useful dressing substitute for temporalis fascia graft due to the reduction in the epithlializing time offered by the AM in revision ear surgery.

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