The authors have no funding, financial relationships, or conflicts of interest to disclose.
A study of the new generation of the advance system tongue implants: Three- and six-month effects of tongue to mandible tethering for obstructive sleep apnea†
Article first published online: 12 OCT 2011
Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 121, Issue 11, pages 2487–2493, November 2011
How to Cite
Pavelec, V., Hamans, E. and Stuck, B. A. (2011), A study of the new generation of the advance system tongue implants: Three- and six-month effects of tongue to mandible tethering for obstructive sleep apnea. The Laryngoscope, 121: 2487–2493. doi: 10.1002/lary.22173
- Issue published online: 21 OCT 2011
- Article first published online: 12 OCT 2011
- Accepted manuscript online: 20 JUL 2011 11:11AM EST
- Manuscript Accepted: 16 MAY 2011
- Manuscript Revised: 12 MAY 2011
- Manuscript Received: 2 JAN 2011
- Obstructive sleep apnea;
- tongue base;
- sleep surgery;
- Level of Evidence: 2.
Treatment of hypopharyngeal collapse of upper airway is a surgical challenge in obstructive sleep apnea (OSA) patients who fail continuous positive airway pressure (CPAP).
A prospective, nonrandomized, multicentered, feasibility study.
Nineteen OSA patients with an apnea-hypopnea index (AHI) between 15 and 50 with CPAP intolerance were included in the study. Baseline polysomnography (PSG) was measured, and 3- and 6-month postoperative PSGs were recorded. Preoperative and postoperative home sleep studies, cephalographs, and videoendoscopy were performed. Additionally, the subjects completed the Epworth Sleepiness Scale (ESS), Patient and Bed Partner Snoring Questionnaire, Functional Outcomes of Sleep Questionnaire, and Throat Questionnaire.
AHI dropped from 33.8 at baseline to 18.6 at 3-month follow-up and to 24.3 at 6-month follow-up, respectively. Overall surgical success was 38.9% as defined by a 50% drop in AHI to a score below 20 at 6 months. ESS decreased from 11.4 to 6.1 and 7.4 at 3 months and 6 months, respectively. Snoring intensity was reduced from 7% to 3.8% at 3 and 6 months, respectively. Quality of life was improved from 15.6 to 17.9 (14.3%) and 18.1 (15.6%) at 3 months and 6 months, respectively.
The rates of surgical success, feasibility, and safety were satisfactory. Further technical device improvement is necessary and must be based on a new understanding of tongue forces.