The authors have no funding, financial relationships, or conflicts of interest to disclose.
Efficacy and safety of acute injection laryngoplasty for vocal cord paralysis following thoracic surgery†
Article first published online: 12 OCT 2011
Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 121, Issue 11, pages 2406–2410, November 2011
How to Cite
Graboyes, E. M., Bradley, J. P., Meyers, B. F. and Nussenbaum, B. (2011), Efficacy and safety of acute injection laryngoplasty for vocal cord paralysis following thoracic surgery. The Laryngoscope, 121: 2406–2410. doi: 10.1002/lary.22178
- Issue published online: 21 OCT 2011
- Article first published online: 12 OCT 2011
- Accepted manuscript online: 11 OCT 2011 10:59AM EST
- Manuscript Accepted: 30 JUN 2011
- Manuscript Revised: 28 JUN 2011
- Manuscript Received: 5 APR 2011
- Injection laryngoplasty;
- vocal cord;
- vocal cord paralysis;
- Level of Evidence: 2b.
The primary objective of this study was to evaluate the effectiveness and safety of injection laryngoplasty using a temporary injectable agent in the acute setting for patients with unilateral vocal cord paralysis following thoracic surgical procedures.
Retrospective consecutive case series in an academic institution.
Inclusion criteria included patients acutely treated with injection laryngoplasty from January 1, 2006, to March 31, 2010, for a unilateral vocal cord paralysis that occurred after a thoracic surgical procedure (N = 20). All patients were injected with Radiesse Voice Gel using microlaryngoscopy technique.
The mean time to vocal cord injection from the time of thoracic surgery was 4.5 days. There was one operative-related complication of intraoperative bile reflux that caused a pneumonitis. Ninety percent of patients were recommended for strict nothing by mouth prior to injection. Of these, 94% were allowed an oral diet following injection, and 67% tolerated a regular diet. None of the patients required subsequent procedures for aspiration or dysphagia, and 25% required further intervention after discharge for persistent dysphonia. Patients with a known nerve transection had a higher rate of dysphonia requiring further surgical procedures than those who did not have a known nerve transection.
Acute treatment of thoracic surgery-related unilateral vocal cord paralysis with injection laryngoplasty appears safe and effective at preventing postoperative aspiration pneumonia and improves swallowing function to allow resumption of an oral diet. A single injection is often the only required treatment.