fMRI evaluation of cochlear implant candidacy in diffuse cortical cytomegalovirus disease


  • Presented at the William House Cochlear Implant Study Group at the American Academy of Otolaryngology–Head and Neck Surgery Foundation, San Francisco, California, U.S.A., Sept 10, 2011.

  • The authors have no funding, financial relationships, or conflicts of interest to disclose.


Congenital cytomegalovirus infection is the most frequent nongenetic cause of pediatric hearing loss in the United States, affecting approximately 8,000 children each year. Due in part to variable cytomegalic involvement of the auditory cortex, cochlear implantation outcomes have varied widely. Functional magnetic resonance imaging (fMRI) has the potential to assist in determining candidacy for cochlear implantation through the detection of intact auditory pathways including the cortex. We report a case of a 21-month-old girl with cytomegalovirus-related deafness and diffuse white matter involvement in which fMRI was a determining factor for cochlear implantation and side selection.