Presented at the Triological Society Combined Sections Meeting, Miami, Florida, U.S.A., January 26–28, 2012.
Version of Record online: 23 MAR 2012
Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 122, Issue 5, pages 970–972, May 2012
How to Cite
Chaudhary, A., Ramchand, T., Frohman, L. P., Liu, J. K. and Eloy, J. A. (2012), Miller fisher variant of guillain-barré syndrome masquerading as acute sphenoid sinusitis with orbital apex syndrome. The Laryngoscope, 122: 970–972. doi: 10.1002/lary.23248
The authors have no funding, financial relationships, or conflicts of interest to disclose.
- Issue online: 18 APR 2012
- Version of Record online: 23 MAR 2012
- Manuscript Accepted: 20 JAN 2012
- Manuscript Received: 9 JAN 2012
- Miller Fisher;
- Miller Fisher syndrome;
- Guillain-Barré syndrome;
- Miller Fisher variant of Guillain-Barré syndrome;
- orbital apex syndrome;
- acute sphenoid sinusitis;
- cavernous sinus thrombosis;
- acute viral sinusitis;
- intracranial complication of sinusitis
Miller Fisher syndrome (MFS), a variant of Guillain-Barré syndrome, is a rare disorder typically characterized by a triad of ataxia, areflexia, and ophthalmoplegia, which may have a highly variable clinical presentation. We report a case of MFS in a 45-year-old female presenting with sphenoid sinusitis and sixth nerve palsy. She underwent endoscopic sphenoid sinusotomy without improvement, had postoperative deterioration, was diagnosed with MFS, and was treated with intravenous immunoglobulin with complete response. Because of the potential severity of Guillain-Barré syndrome, great vigilance should be taken when examining sixth nerve palsies to prevent misdiagnosis and delay in treatment of the MFS variant of this disease.