Presented at the Annual Meeting of the American Academy of Otolaryngology–Head and Neck Surgery Foundation, San Francisco, California, U.S.A., September 10–14, 2011.
Community-acquired methicillin-resistant Staphylococcus aureus skull base osteomyelitis with occipital condylar cerebrospinal fluid leak in an immunocompetent patient†
Article first published online: 23 MAR 2012
Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 122, Issue 5, pages 977–981, May 2012
How to Cite
Tomovic, S., Friedel, M. E., Liu, J. K. and Eloy, J. A. (2012), Community-acquired methicillin-resistant Staphylococcus aureus skull base osteomyelitis with occipital condylar cerebrospinal fluid leak in an immunocompetent patient. The Laryngoscope, 122: 977–981. doi: 10.1002/lary.23253
- Issue published online: 18 APR 2012
- Article first published online: 23 MAR 2012
- Manuscript Accepted: 30 JAN 2012
- Manuscript Revised: 25 JAN 2012
- Manuscript Received: 10 JAN 2012
- Skull base osteomyelitis;
- acute rhinosinusitis;
- cerebrospinal fluid leakage;
- bacterial rhinosinusitis;
- endoscopic sinus surgery;
- endoscopic skull base surgery;
Community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is emerging as an important pathogen in paranasal sinus disease. However, sinonasal CA-MRSA has not been reported as a source of central skull base osteomyelitis. We report an unusual case of a previously healthy and immunocompetent adult who developed meningitis, central skull base osteomyelitis, and occipital condylar cerebrospinal fluid rhinorrhea from CA-MRSA sphenoid sinusitis requiring endoscopic surgical repair. This case clearly demonstrates the expanding spectrum of severe infections caused by CA-MRSA, which requires prompt diagnosis, a high level of suspicion, and appropriate medical and/or surgical management.