The authors have no funding, financial relationships, or conflicts of interest to disclose.
Head and Neck
The effect of smoking on perioperative complications in head and neck oncologic surgery†
Version of Record online: 2 JUL 2012
Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 122, Issue 8, pages 1800–1808, August 2012
How to Cite
Lassig, A. A. D., Yueh, B. and Joseph, A. M. (2012), The effect of smoking on perioperative complications in head and neck oncologic surgery. The Laryngoscope, 122: 1800–1808. doi: 10.1002/lary.23308
- Issue online: 25 JUL 2012
- Version of Record online: 2 JUL 2012
- Accepted manuscript online: 22 MAR 2012 10:18AM EST
- Manuscript Accepted: 23 FEB 2012
- Manuscript Revised: 1 FEB 2012
- Manuscript Received: 21 NOV 2011
- Head and neck cancer;
Cigarette smoking is the most important risk factor for head and neck cancer. Conventional wisdom suggests that smoking causes increased postoperative wound healing and systemic complications in this patient population, but it is unclear if the clinical literature supports this.
The authors performed a review of the literature from 1990 to 2010 on the effect of cigarette smoking on perioperative complications in head and neck surgery.
Thirty-six articles met eligibility criteria and were reviewed; 14 focused on extirpative surgery and 22 on reconstruction. Most of the evidence was comprised of case series and small cohort studies. We reviewed local wound healing and systemic complications, and 47% of studies supported an association between smoking and complications of surgery.
Evidence from the existing clinical literature is inconclusive on an association between cigarette smoking and perioperative complications after head and neck surgery. The negative impact of smoking is suggested; however, the majority of articles had significant methodological weaknesses. Prospective study of tobacco-induced complications is needed.