Presented in part at the 219th Meeting of the Netherlands Society for Otorhinolaryngology, Head and Neck Surgery, Groningen, the Netherlands, November 17–18, 2011.
Article first published online: 7 MAY 2012
Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.
Volume 122, Issue 8, pages 1826–1830, August 2012
How to Cite
Tjon Pian Gi, R. E. A., Halmos, G. B., van Hemel, B. M., van den Heuvel, E. R., van der Laan, B. F. A. M., Plaat, B. E. C. and Dikkers, F. G. (2012), Narrow band imaging is a new technique in visualization of recurrent respiratory papillomatosis. The Laryngoscope, 122: 1826–1830. doi: 10.1002/lary.23344
Medical equipment was supplied by Olympus Netherlands during the period of this study. The authors have no other funding, financial relationships, or conflicts of interest to disclose.
- Issue published online: 25 JUL 2012
- Article first published online: 7 MAY 2012
- Accepted manuscript online: 5 APR 2012 04:55AM EST
- Manuscript Accepted: 14 MAR 2012
- Manuscript Revised: 8 FEB 2012
- Manuscript Received: 9 DEC 2011
- narrow band imaging;
- laryngeal papillomatosis;
- recurrent respiratory papillomatosis;
- Level of Evidence: 4
Recurrent respiratory papillomatosis (RRP) is a rare, benign, wart-like disease for which no curative treatment exists. The goal of treatment is total surgical removal of the epithelial lesions to keep the airway open and the voice sufficient. Therefore, it is essential to visualize all papillomatous lesions. The present study aims to evaluate the sensitivity of additional use of narrow band imaging (NBI) in detecting RRP during microlaryngoscopy.
Between January 2011 and July 2011, patients with RRP underwent systematic inspection during microlaryngoscopy using conventional white light (WL) immediately followed by inspection with NBI. Consensus was achieved about the number of lesions and number of RRP suspect lesions. All lesions were subsequently excised and sent for histopathological examination.
Eighty-six excisional biopsies were taken in 24 microlaryngoscopies performed in 14 RRP patients. Eleven out of the 13 additional biopsies taken, induced by the second inspection with NBI, proved to be papillomata after histopathological examination. The sensitivity increased from 80% with WL up to 97% with WL + NBI (P < .01), whereas the specificity remained poor (32% and 28%, respectively).
NBI is an additional diagnostic tool in increasing the sensitivity of visualizing papillomata during microlaryngoscopy. Laryngoscope, 2012