Get access

A pilot study of segmental mandibulectomy with surgical navigation using fluorine-18 fluorodeoxyglucose positron-emission tomography/computed tomography

Authors

  • Chih-Yen Chien MD, FACS,

    Corresponding author
    1. Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    2. Kaohsiung Chang Gung Head and Neck Oncology Group, Cancer Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    • 123Ta-Pei Road, Niao-Song District, Kaohsiung, 833, Taiwan
    Search for more papers by this author
  • Hui-Ching Chuang MD, PhD,

    1. Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    2. Kaohsiung Chang Gung Head and Neck Oncology Group, Cancer Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Search for more papers by this author
  • Shu-Hua Huang MD,

    1. Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    2. Kaohsiung Chang Gung Head and Neck Oncology Group, Cancer Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Search for more papers by this author
  • Wei-Che Lin MD,

    1. Department of Diagnostic Radiation, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    2. Kaohsiung Chang Gung Head and Neck Oncology Group, Cancer Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Search for more papers by this author
  • Husan-Ying Huang MD

    1. Department of Pathology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    2. Kaohsiung Chang Gung Head and Neck Oncology Group, Cancer Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Search for more papers by this author

  • Presented at the Third World Congress of the International Academy of Oral Oncology, Singapore, July 15, 2011.

  • The authors have no funding, financial relationships, or conflicts of interest to disclose.

Abstract

Objectives/Hypothesis:

To evaluate the efficacy of treating lower gum cancer using fluorine-18 fluorodeoxyglucose positron-emission tomography/computed tomography ([18] F-FDG PET/CT) surgical navigation to control bony margins during segmental mandibulectomy.

Study Design:

This study was conducted between September 2010 and June 2011 in a tertiary referral center in southern Taiwan.

Methods:

Segmental mandibulectomy was performed using surgical navigation via [18] F-FDG PET/CT. Bony margins after decalcification, the 1-year survival rate, and local control rate were evaluated.

Results:

Ten cases of advanced lower gum cancer in male patients were treated by mandibulectomy, and the bony margins required to excise all neoplastic cells were negative in all cases by using surgical navigation. The minimal distance from the tumor border to the bony incision was 2 cm (2.0–2.9 cm). The mean follow-up period was 15.2 months (range, 6–24 months) with a 1-year survival rate of 90% and local control rate of 100%.

Conclusions:

The segmental mandibulectomy aided by surgical navigation with [18] F-FDG PET/CT guidance is simple and feasible to ensure adequate bony margins intraoperatively, but more patients are necessary to support these findings.

Get access to the full text of this article

Ancillary