Presented at Triological Society Combined Sections Meeting, Miami Beach, Florida, U.S.A., January 26–28, 2012.
Interarytenoid botulinum toxin injection for recalcitrant vocal process granuloma
Article first published online: 20 SEP 2013
Copyright © 2013 The American Laryngological, Rhinological and Otological Society, Inc.
Volume 123, Issue 12, pages 3084–3087, December 2013
How to Cite
Fink, D. S., Achkar, J., Franco, R. A. and Song, P. C. (2013), Interarytenoid botulinum toxin injection for recalcitrant vocal process granuloma. The Laryngoscope, 123: 3084–3087. doi: 10.1002/lary.23915
Research was performed at the Massachusetts Eye and Ear Infirmary, Boston, M.A., U.S.A. The authors have no other funding, financial relationships, or conflicts of interest to disclose.
- Issue published online: 25 NOV 2013
- Article first published online: 20 SEP 2013
- Manuscript Accepted: 5 NOV 2012
- vocal process
This study evaluated the efficacy of botulinum toxin type A injected into the interarytenoid muscle to treat recalcitrant vocal process granulomas.
Retrospective clinical review at a tertiary care center.
Eight patients with vocal process granulomas refractory to a variety of prior treatments including surgical resection, proton pump inhibitor therapy, and voice therapy underwent percutaneous injection of botulinum toxin type A into the interarytenoid muscle, performed in an office setting. Doses ranged from 5 U to 25 U in one to two injections.
One patient demonstrated no improvement, two patients demonstrated partial resolution, and five patients demonstrated complete resolution of their granulomas. Four patients noted transient breathiness. There were no other side effects. All patients tolerated the injections without difficulty.
Botulinum toxin injection into the interarytenoid muscle appears to be a safe and effective modality for treating recalcitrant vocal process granuloma. Laryngoscope, 123:3084–3087, 2013