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Serial computed tomographic and positron emission tomographic properties of injection material used for vocal fold augmentation

Authors

  • Tack-Kyun Kwon MD,

    Corresponding author
    1. Research Center for Sensory Organs, Seoul National University Medical Research Center, Seoul, South Korea
    • Department of Otorhinolaryngology–Head and Neck Surgery, Seoul National University, College of Medicine, Seoul, South Korea
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  • Ji-Eun Lee MD,

    1. Department of Otorhinolaryngology–Head and Neck Surgery, Seoul National University, College of Medicine, Seoul, South Korea
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  • Won Jae Cha MD,

    1. Department of Otorhinolaryngology–Head and Neck Surgery, Seoul National University, College of Medicine, Seoul, South Korea
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  • Chang Myeon Song MD,

    1. Department of Otorhinolaryngology–Head and Neck Surgery, Seoul National University, College of Medicine, Seoul, South Korea
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  • Myung-Whun Sung MD,

    1. Department of Otorhinolaryngology–Head and Neck Surgery, Seoul National University, College of Medicine, Seoul, South Korea
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  • Kwang Hyun Kim MD

    1. Department of Otorhinolaryngology–Head and Neck Surgery, Seoul National University, College of Medicine, Seoul, South Korea
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  • The authors have no funding, financial relationships, or conflicts of interest to disclose.

Send correspondence to Tack-Kyun Kwon, MD, PhD, Department of Otolaryngology–Head and Neck Surgery, 10th Floor, Seoul National University Hospital, 28 Yongon-Dong, Chongno-Gu, Seoul, 110-744, South Korea. E-mail: kwontk@snu.ac.kr

Abstract

Objectives/Hypothesis

This study aimed to demonstrate the radiological properties of hyaluronic acid (HA) and calcium hydroxylapatite (CAHA) on serial computed tomography (CT) and positron emission tomography (PET) scan.

Study Design

Retrospective Case Series.

Method

Retrospective chart and imaging analysis of patients who underwent HA or CAHA injection laryngoplasty.

Result

Total of 243 patients who underwent more than one CT of PET after last injection laryngoplasty were included. Sixty-eight patients received HA injection and 175 patients received CAHA injection. In all cases HA showed hypo-density in CT and no abnormal uptake on PET. CAHA showed bright calcific density on CT scan and high uptake on PET but had disappeared with time in 18 months if injected less than 0.85 mL in amount.

Conclusion

These findings support previous clinical studies on CAHA longevity and provide proper radiological interpretation on injection materials in the vocal folds.

Level of Evidence

IV (Case series) Laryngoscope, 123:2491–2496, 2013

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