The authors have no funding, financial relationships, or conflicts of interest to disclose.
Long-term results of endoscopic sinus surgery–oriented treatment for chronic rhinosinusitis with asthma
Article first published online: 5 AUG 2013
© 2013 The American Laryngological, Rhinological and Otological Society, Inc.
Volume 124, Issue 1, pages 24–28, January 2014
How to Cite
Chen, F.-H., Zuo, K.-J., Guo, Y.-B., Li, Z.-P., Xu, G., Xu, R. and Shi, J.-B. (2014), Long-term results of endoscopic sinus surgery–oriented treatment for chronic rhinosinusitis with asthma. The Laryngoscope, 124: 24–28. doi: 10.1002/lary.24196
- Issue published online: 20 DEC 2013
- Article first published online: 5 AUG 2013
- Accepted manuscript online: 20 MAY 2013 03:08AM EST
- Manuscript Accepted: 19 APR 2013
- Manuscript Revised: 17 MAR 2013
- Manuscript Received: 23 FEB 2013
- This study was supported by grants from the National Natural Science Grant of China (81071030, 81170896, 31270967, 81272062, 81273272, and 81271055) and Guangdong Province Technology Projects (No. 2010B031600088).
- Chronic rhinosinusitis;
- nasal polyps;
- aspirin intolerance;
- sinus surgery
The aims of this study were to evaluate the efficacy of functional endoscopic sinus surgery (FESS)–oriented multimodality treatment in chronic rhinosinusitis (CRS) patients with asthma and its impact on asthma.
Prospective, nonrandomized cohort.
Twenty-seven CRS patients with asthma who underwent FESS with postoperative topical corticosteroid spray were evaluated preoperatively; 25 of them were evaluated 1 year and 3 years postoperatively. CRS was evaluated by visual analogue scale, clinical control of CRS, and objective measurement endoscopy Lund-Kennedy scores. Asthma was assessed by subjective asthma control test and asthma control level, also by objective antiasthma medication use and pulmonary function tests.
VAS scores of general symptoms (8.09 ± 0.87 preoperatively) were significantly improved at 1 year (2.94 ± 2.21) and 3 years (3.77 ± 2.16) postoperation (P = .000). No difference in these items was found between 1 year and 3 years (P = .463). Endoscopy Lund-Kennedy scores at 1 year (4.34 ± 3.09) and 3 years (5.80 ± 3.38) postoperatively were significantly better (9.33 ± 2.03 preoperatively, P = .000), and there was no difference between 1 year and 3 years of follow-up (P > .05). Significantly, asthma control level improved postoperatively (P = .025). However, antiasthma drug and pulmonary function showed no significant change postoperatively (P > .05).
FESS-oriented multimodality treatment improves CRS with asthma significantly and persistently. Asthma control level improved. Antiasthma medication use and pulmonary function remained stable.
Level of Evidence
4. Laryngoscope, 124:24–28, 2014