Patient-based outcomes of in-office KTP ablation of vocal fold polyps

Authors

  • Shaum Sridharan MD,

    1. NYU Voice Center, Department of Otolaryngology–Head and Neck Surgery, New York University School of Medicine, New York, New York
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  • Stratos Achlatis MD,

    1. NYU Voice Center, Department of Otolaryngology–Head and Neck Surgery, New York University School of Medicine, New York, New York
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  • Ryan Ruiz BA,

    1. NYU Voice Center, Department of Otolaryngology–Head and Neck Surgery, New York University School of Medicine, New York, New York
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  • Seema Jeswani MD,

    1. NYU Voice Center, Department of Otolaryngology–Head and Neck Surgery, New York University School of Medicine, New York, New York
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  • Yixin Fang PhD,

    1. Division of Biostatistics, Department of Population Health, New York University School of Medicine, New York, New York, U.S.A.
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  • Ryan C. Branski PhD,

    Corresponding author
    1. NYU Voice Center, Department of Otolaryngology–Head and Neck Surgery, New York University School of Medicine, New York, New York
    • Send correspondence to Ryan C. Branski, PhD, Director, NYU Voice Center, 345 East 37th Street, Suite 306, New York, NY 10016. E-mail: ryan.branski@nyumc.org

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  • Milan R. Amin MD

    1. NYU Voice Center, Department of Otolaryngology–Head and Neck Surgery, New York University School of Medicine, New York, New York
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  • Presented at the American Laryngologic Association/Combined Otolaryngologic Spring Meetings, Orlando, Florida, U.S.A., April 10–14, 2013.

  • The authors have no funding, financial relationships, or conflicts of interest to disclose.

Abstract

Objectives/Hypothesis

Recent data have suggested that in-office potassium titanyl phosphate (KTP) laser treatment for benign vocal fold lesions yields significant reduction in lesion size with favorable effects on both mucosal wave and glottic closure. However, these previous studies omitted voice-related outcomes. We sought to compliment these previous data with voice-related outcomes in a cohort of patients undergoing KTP ablation of vocal fold polyps.

Study Design

Retrospective outcomes study.

Methods

Voice Handicap Index (VHI)−10 and acoustic measures were reviewed for 31 consecutive patients with benign vocal fold polyps treated with in-office KTP laser surgery. All data were analyzed statistically via a mixed model fit to analyze the data from each of three clinical visits.

Results

Across all patients, the mean VHI-10 scores decreased at first follow-up from 19.7 to 9.7 (P < .0001). At subsequent follow-up visits, the VHI-10 scores remained stable (mean, 8.3). This shift in VHI scores was accompanied by favorable improvements in both noise-to-harmonic ratio and speaking fundamental frequency in both males and females.

Conclusions

In-office KTP ablation of vocal fold polyps had a favorable effect on patient-reported handicap as determined by the VHI-10. This treatment also slightly altered physiologic measures of voice; however, these measures did not achieve statistical significance.

Level of Evidence

4. Laryngoscope, 124:1176–1179, 2014

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