Presented orally at the 2013 annual meeting of the American Laryngological Association, Orlando, Florida, U.S.A., April 10–11, 2013.
Voice quality after treatment of T1a glottic cancer
Version of Record online: 13 NOV 2013
© 2013 The American Laryngological, Rhinological and Otological Society, Inc.
Volume 124, Issue 6, pages 1398–1401, June 2014
How to Cite
Laoufi, S., Mirghani, H., Janot, F. and Hartl, D. M. (2014), Voice quality after treatment of T1a glottic cancer. The Laryngoscope, 124: 1398–1401. doi: 10.1002/lary.24445
The authors have no funding, financial relationships, or conflicts of interest to disclose.
- Issue online: 27 MAY 2014
- Version of Record online: 13 NOV 2013
- Accepted manuscript online: 1 OCT 2013 07:40AM EST
- Manuscript Accepted: 20 SEP 2013
- Manuscript Revised: 10 SEP 2013
- Manuscript Received: 15 FEB 2013
- Glottic cancer;
- squamous cell carcinoma;
- quality of life;
- voice handicap
To compare voice handicap and quality of life after radiotherapy (RT) versus transoral laser surgery (LS) for T1a glottic carcinoma.
Retrospective study (1996–2011) of patients treated with RT or LS for T1a glottic squamous cell carcinoma with curative intent.
Disease-free patients were assessed using Voice Handicap Index (VHI 30) and European Organization for Research and Treatment of Cancer Head and Neck Quality of Life (EORTC QLQ-HN35) questionnaires.
Of 147 patients, 95 (65%) completed the questionnaires: fifty-one patients an average of 8 years after RT and 44 patients an average of 4 years after LS (no difference in age or sex ratio). The average total VHI 30 was 13.1 for RT and 29.2 for LS (P < .0001), with average emotional, physical and functional subscores significantly different. The average total EORTC QLQ-HN35 was 37.7 for RT versus 40.7 for LS (P = .7), with a difference only in the speaking subscore (P = .04).
Long-term subjective voice-related quality of life was worse after LS, with no difference in other domains. These results should be interpreted in light of the biases inherent in retrospective studies.
Level of Evidence
4. Laryngoscope, 124:1398–1401, 2014