The authors have no funding, financial relationships, or conflicts of interest to disclose.
Comorbidity profile of chronic rhinosinusitis: A population-based study
Version of Record online: 11 FEB 2014
© 2014 The American Laryngological, Rhinological and Otological Society, Inc.
Volume 124, Issue 7, pages 1536–1541, July 2014
How to Cite
Chung, S.-D., Chen, P.-Y., Lin, H.-C. and Hung, S.-H. (2014), Comorbidity profile of chronic rhinosinusitis: A population-based study. The Laryngoscope, 124: 1536–1541. doi: 10.1002/lary.24581
- Issue online: 20 JUN 2014
- Version of Record online: 11 FEB 2014
- Accepted manuscript online: 3 JAN 2014 03:04AM EST
- Manuscript Accepted: 30 DEC 2013
- Manuscript Revised: 6 DEC 2013
- Manuscript Received: 18 OCT 2013
- Chronic rhinosinusitis;
This study aimed to explore the prevalence of a broad spectrum of comorbid medical conditions among patients with chronic rhinosinusitis (CRS), using a population-based dataset.
A cross-sectional study.
In total, 5,734 CRS subjects and 17,202 comparison subjects were included in this study. Separate conditional logistic regression analyses were performed to calculate the odds ratio (OR) for each of 39 medical comorbidities between subjects with and without CRS.
For 27 of the 39 study comorbidities, results showed that subjects with CRS had a statistically significantly higher OR than subjects without CRS after adjusting for sociodemographic characteristics. Ranks of the top five comorbid relationships from the strongest ORs to the lowest were as follows: asthma (OR = 3.09), chronic pulmonary disease (OR = 3.04), weight loss (OR = 2.58), obesity (OR = 2.50), and migraines (OR = 2.30).
Our results indicate that subjects with CRS have an increased prevalence of various comorbidities.
Level of Evidence
3b. Laryngoscope, 124:1536–1541, 2014