Each author took part in the creation and revision of this manuscript. The original clinical studies were funded by an unrestricted grant from Reliant Technologies. The study extension was departmentally funded.
Article first published online: 17 FEB 2010
Copyright © 2010 Wiley-Liss, Inc.
Lasers in Surgery and Medicine
Volume 42, Issue 2, pages 168–170, February 2010
How to Cite
Ortiz, A. E., Tremaine, A. M. and Zachary, C. B. (2010), Long-term efficacy of a fractional resurfacing device. Lasers Surg. Med., 42: 168–170. doi: 10.1002/lsm.20885
The authors have no conflicts of interest to disclose.
The information in this paper was presented at the 2009 American Society for Laser Medicine and Surgery Annual Conference in National Harbor, Maryland and at the International Society of Cosmetic and Laser Surgeons, Inc. 17th International Symposium on Cosmetic Laser Surgery in Scottsdale, Arizona.
- Issue published online: 17 FEB 2010
- Article first published online: 17 FEB 2010
- Manuscript Accepted: 17 NOV 2009
- Reliant Technologies
- acne scar;
- CO2 laser;
- fractional photothermolysis;
- skin resurfacing;
- fractional deep dermal ablation;
- ablative resurfacing
Background and Objective
Recently, there has been much debate regarding the long-term efficacy of fractional resurfacing devices. While pulsed CO2 laser resurfacing is considered a highly effective treatment, fractionated resurfacing is a newer modality and its long-term efficacy has yet to be assessed. We report the long-term outcomes of subjects previously treated with fractional CO2 resurfacing for photodamaged skin and acne scars.
Study Design/Materials and Methods
Ten subjects from our previous studies who received fractional resurfacing for the treatment of acne scarring and photodamage returned for long-term follow-up visits at 1 and 2 years, respectively. Investigators graded maintenance of improvement on a quartile scale based on clinical photography.
Subjects maintained 74% of their overall improvement at their long-term visits compared to 3-month follow-up visits. While clinical improvement was maintained long-term, the results were not as remarkable as those seen at 3-month visits. The authors speculate that results seen at 3 months may be enhanced by persistent inflammatory changes, as evidenced by heat shock protein 47 activity and ongoing collagen remodeling seen in previous histologic studies. Relaxation of tightening is to be expected with any procedure along with the natural progression of aging. However, patient satisfaction was upheld long-term.
Fractional CO2 laser resurfacing does have long-term efficacy and persistence of improvement of acne scarring and photodamage compared to baseline. However, additional treatments may be necessary to enhance long-term results. Lasers Surg. Med. 42:168–170, 2010. © 2010 Wiley-Liss, Inc.