Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported
High-intensity diode laser in combination with bipolar transurethral resection of the prostate: A new strategy for the treatment of large prostates (>80 ml)†
Article first published online: 27 SEP 2012
Copyright © 2012 Wiley Periodicals, Inc.
Lasers in Surgery and Medicine
Volume 44, Issue 9, pages 699–704, November 2012
How to Cite
Chen, C.-H., Chiang, P.-H., Lee, W.-C., Chuang, Y.-C., Kang, C.-H., Hsu, C.-C., Lee, W.-C., Chen, Y.-T. and Cheng, Y.-T. (2012), High-intensity diode laser in combination with bipolar transurethral resection of the prostate: A new strategy for the treatment of large prostates (>80 ml). Lasers Surg. Med., 44: 699–704. doi: 10.1002/lsm.22081
- Issue published online: 18 OCT 2012
- Article first published online: 27 SEP 2012
- Manuscript Accepted: 7 SEP 2012
- benign prostatic hyperplasia;
- diode laser;
- large prostate;
- transurethral resection of the prostate (TURP)
Background and Objective
The ideal treatment of large prostates with symptomatic benign prostatic hyperplasia (BPH) remains controversial. We compare the efficacy and safety of monopolar transurethral resection of the prostate (TURP) with high-intensity diode laser in combination with bipolar TURP (DL + b-TURP) in the treatment of large prostates.
Materials and Methods
We retrospectively analyzed all patients with lower urinary tract symptoms (LUTS) secondary to BPH with prostates larger than 80 ml, undergoing monopolar TURP (n = 36) or DL + b-TURP (n = 37) between January 2008 and March 2010. The preoperative and follow-up functional parameters including International Prostate Symptom Score (IPSS), post-void residual urine (PVR), maximum flow rate (Qmax), quality of life score (QoLs), prostate size, and prostate-specific antigen (PSA) were assessed. The operative data, peri- and post-operative complications were also recorded.
The demographic data were comparable between the two groups. Preoperative prostate volume was 110.8 ± 28.9 ml in the DL + b-TURP group and 103.7 ± 31.2 ml in the TURP group. TURP group had significantly shorter operative time; however, the catheterization time and hospital stay were in favor of the DL + b-TURP group (P < 0.001). The decrease in hemoglobin was statistically significantly greater in the TURP group. Late complications were also comparable. Both groups could achieve significant improvements in functional outcomes during the follow-up of 24 months.
With regard to the operative safety and functional results, high-intensity diode laser combined with bipolar TURP is feasible for BPH treatment with large prostates. Lasers Surg. Med. 44: 699–704, 2012. © 2012 Wiley Periodicals, Inc.