• 1
    Pisani P, Parkin DM, Ferlay J. Estimates of the worldwide mortality from eighteen major cancers in 1985. Implications for prevention and projections of future burden. Int J Cancer 1993; 55: 891903.
  • 2
    Bosch F. Global epidemiology of hepatocellular carcinoma. In: TaborE, editor. Liver cancer. New York: Churchill Livingstone; 1997. p 1328.
  • 3
    El-Serag HB. Epidemiology of hepatocellular carcinoma. Clin Liver Dis 2001; 5: 87107, vi.
  • 4
    Pal S, Pande GK. Current status of surgery and transplantation in the management of hepatocellular carcinoma: an overview. J Hepatobiliary Pancreat Surg 2001; 8: 323336.
  • 5
    Greenlee RT, Hill-Harmon MB, Murray T, Thun M. Cancer statistics, 2001. CA Cancer J Clin 2001; 51: 1536.
  • 6
    McKean-Cowdin R, Feigelson HS, Ross RK, Pike MC, Henderson BE. Declining cancer rates in the 1990s. J Clin Oncol 2000; 18: 22582268.
  • 7
    Liver Cancer Study Group of Japan. Primary liver cancer in Japan.Clinicopathologic features and results of surgical treatment. Ann Surg 1990; 211: 277287.
  • 8
    Arii S, Yamaoka Y, Futagawa S, Inoue K, Kobayashi K, Kojiro M, et al. Results of surgical and nonsurgical treatment for small-sized hepatocellular carcinomas: a retrospective and nationwide survey in Japan. Liver Cancer Study Group of Japan. Hepatology 2000; 32: 12241229.
  • 9
    Colombo M. Hepatocellular carcinoma in cirrhotics. Semin Liver Dis 1993; 13: 374383.
  • 10
    Barbara L, Benzi G, Gaiani S, Fusconi F, Zironi G, Siringo S, et al. Natural history of small untreated hepatocellular carcinoma in cirrhosis: a multivariate analysis of prognostic factors of tumor growth rate and patient survival. Hepatology 1992; 16: 132137.
  • 11
    Nagorney DM, van Heerden JA, Ilstrup DM, Adson MA. Primary hepatic malignancy: surgical management and determinants of survival. Surgery 1989; 106: 740748; discussion 748–749.
  • 12
    Lai EC, Ng IO, Ng MM, Lok AS, Tam PC, Fan ST, et al. Long-term results of resection for large hepatocellular carcinoma: a multivariate analysis of clinicopathological features. Hepatology 1990; 11: 815818.
  • 13
    Kosuge T, Makuuchi M, Takayama T. Long-term results after resection of hepatocellular carcinoma: experience of 480 cases. Hepatogastroenterology 1993; 40: 328332.
  • 14
    Fong Y, Sun RL, Jarnagin W, Blumgart LH. An analysis of 412 cases of hepatocellular carcinoma at a Western center. Ann Surg 1999; 229: 790799; discussion 799–800.
  • 15
    A new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients: the Cancer of the Liver Italian Program (CLIP) investigators. Hepatology 1998; 28: 751755.
  • 16
    Vauthey JN, Klimstra D, Franceschi D, Tao Y, Fortner J, Blumgart LH, et al. Factors affecting long-term outcome after hepatic resection for hepatocellular carcinoma. Am J Surg 1995; 169: 2834; discussion 34–25.
  • 17
    Okuda K, Ohtsuki T, Obata H, Tomimatsu M, Okazaki N, Hasegawa H, et al. Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients. Cancer 1985; 56: 918928.
  • 18
    Prospective validation of the CLIP score: a new prognostic system for patients with cirrhosis and hepatocellular carcinoma. Cancer of the Liver Italian Program (CLIP) Investigators. Hepatology 2000; 31: 840845.
  • 19
    Llovet JM, Bru C, Bruix J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin Liver Dis 1999; 19: 329338.
  • 20
    Cance WG, Stewart AK, Menck HR. The National Cancer Data Base Report on treatment patterns for hepatocellular carcinomas: improved survival of surgically resected patients, 1985–1996. Cancer 2000; 88: 912920.
  • 21
    Liver (including intrahepatic bile ducts). In: GreenF, PageD, FlemingI, et al., editors. AJCC Cancer Staging Handbook, 6th ed. New York: Springer; 2002. p 131144.
  • 22
    Vauthey JN, Lauwers GY, Esnaola NF, Do KA, Belghiti J, Mirza N, et al. Simplified staging for hepatocellular carcinoma. J Clin Oncol 2002; 20: 15271536.
  • 23
    Hermanek P, Hendson DE, Hutter RVP. TNM supplement 1993: a commentary on uniform use. Berlin: Springer; 1993. p 33.
  • 24
    Ikai I, Yamamoto Y, Yamamoto N, Terajima H, Hatano E, Shimahara Y, et al. Results of hepatic resection for hepatocellular carcinoma invading major portal and/or hepatic veins. Surg Oncol Clin N Am 2003; 12: 6575.
  • 25
    Tsai TJ, Chau GY, Lui WY, Tsay SH, King KL, Loong CC, et al. Clinical significance of microscopic tumor venous invasion in patients with resectable hepatocellular carcinoma. Surgery 2000; 127: 603608.
  • 26
    el-Assal ON, Yamanoi A, Soda Y, Yamaguchi M, Yu L, Nagasue N. Proposal of invasiveness score to predict recurrence and survival after curative hepatic resection for hepatocellular carcinoma. Surgery 1997; 122: 571577.
  • 27
    Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F, et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22: 696699.
  • 28
    Yamamoto J, Kosuge T, Takayama T, Shimada K, Yamasaki S, Ozaki H, et al. Recurrence of hepatocellular carcinoma after surgery. Br J Surg 1996; 83: 12191222.
  • 29
    Sasaki Y, Imaoka S, Masutani S, Ohashi I, Ishikawa O, Koyama H, et al. Influence of coexisting cirrhosis on long-term prognosis after surgery in patients with hepatocellular carcinoma. Surgery 1992; 112: 515521.
  • 30
    Nagasue N, Uchida M, Makino Y, Takemoto Y, Yamanoi A, Hayashi T, et al. Incidence and factors associated with intrahepatic recurrence following resection of hepatocellular carcinoma. Gastroenterology 1993; 105: 488494.
  • 31
    Bilimoria M, Lauwers GY, Doherty D. Underlying liver disease but not tumor factors predict long-term survival after hepatic resection of hepatocellular carcinoma. Arch Surg 2001; 136: 528535.
  • 32
    Vauthey JN, Walsh GL, Vlastos G, Lauwers GY. Importance of field cancerisation in clinical oncology. Lancet Oncol 2000; 1: 1516.
  • 33
    Poon RT, Fan ST. Evaluation of the new AJCC/UICC staging system for hepatocellular carcinoma after hepatic resection in Chinese patients. Surg Oncol Clin N Am 2003; 12: 3550.
  • 34
    Fleming I, Cooper J, Henson D. Liver AJCC cancer staging manual, 5th edition Philadelphia: Lippincott-Raven; 1997.
  • 35
    Esnaola N, Mirza N, Lauwers G, Iwao I, Regimbeau J, Belghiti J, et al. Comparison of clinicopathologic characteristics and outcomes after resection in patients with hepatocellular carcinoma treated in the United States, France, and Japan. Ann Surg 2003; 238: 711719.
  • 36
    Bismuth H, Chiche L, Castaing D. Surgical treatment of hepatocellular carcinomas in noncirrhotic liver: experience with 68 liver resections. World J Surg 1995; 19: 3541.
  • 37
    El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 1999; 340: 745750.
  • 38
    Ezaki T, Stansby G, Hobbs K. Regional differences in hepatocellular carcinoma and its surgical treatment. HPB Surg 1991; 4: 121128.
  • 39
    Simonetti RG, Camma C, Fiorello F, Politi F, D'Amico G, Pagliaro L. Hepatocellular carcinoma.A worldwide problem and the major risk factors. Dig Dis Sci 1991; 36: 962972.
  • 40
    Chu CM. Natural history of chronic hepatitis B virus infection in adults with emphasis on the occurrence of cirrhosis and hepatocellular carcinoma. J Gastroenterol Hepatol 2000; 15 (Suppl): E2530.
  • 41
    Merican I, Guan R, Amarapuka D, Alexander MJ, Chutaputti A, Chien RN, et al. Chronic hepatitis B virus infection in Asian countries. J Gastroenterol Hepatol 2000; 15: 13561361.
  • 42
    Di Bisceglie AM, Carithers RL Jr, Gores GJ. Hepatocellular carcinoma. Hepatology 1998; 28: 11611165.
  • 43
    Ahmad SA, Abdalla EK, Spitz FR, Bouvet M, Yahanda AM. Hepatobiliary cancers. In: FeigBW, BergerDH, FuhrmanGM, editors. The M.D. Anderson Surgical Oncology Handbook. Philadelphia: Lippincott Williams & Wilkins; 2003. p 266302.
  • 44
    Vauthey JN, Lauwers GY. Prognostic factors after resection of hepatocellular carcinoma: are there landmarks in the wild forest? J Hepatol 2003; 38: 237239.