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Liver transplantation in patients with HIV infection
Article first published online: 20 SEP 2004
Copyright © 2004 American Association for the Study of Liver Diseases
Supplement: Summary Report of a National Conference: Evolving Concepts in Liver Allocation in the MELD and PELD Era From the October 29, 2004 AASLD/ILTS Transplant Course
Volume 10, Issue Supplement 10S, pages S39–S53, October 2004
How to Cite
Fung, J., Eghtesad, B., Patel-Tom, K., DeVera, M., Chapman, H. and Ragni, M. (2004), Liver transplantation in patients with HIV infection. Liver Transpl, 10: S39–S53. doi: 10.1002/lt.20261
- Issue published online: 21 SEP 2004
- Article first published online: 20 SEP 2004
- 1Liver transplantation for human immunodeficiency virus (HIV)-positive patients with end-stage liver disease in the era of highly active retroviral therapy has proven to be an effective treatment. The concerns of HIV progression have not been borne out by the growing worldwide experience.
- 2CD4 counts are stable and HIV viral load is controllable with medication following liver transplantation.
- 3Hepatitis C virus (HCV) coinfection in HIV-positive recipients is universal, but the severity of recurrence does not appear to be different from that in HIV-negative patients with HCV liver disease.
- 4Complex pharmacokinetic interactions between the calcineurin inhibitors used for immunosuppression along with protease inhibitors are present, but management directed at recognizing the need for monitoring levels does not appear to increase the risk of toxicity.
- 5The degree of immunosuppression from iatrogenic drug therapy and HIV does not lead to increased risk of infectious complications. (Liver Transpl 2004;10:S39–S53.)