Telephone: 81-3-3815-5411; FAX: 81-3-5684-3989
Selection of liver-transplant candidates for adult-to-adult living donor liver transplantation as the only surgical option for end-stage liver disease†
Article first published online: 5 APR 2006
Copyright © 2006 American Association for the Study of Liver Diseases
Volume 12, Issue 7, pages 1077–1083, July 2006
How to Cite
Yamashiki, N., Sugawara, Y., Tamura, S., Kaneko, J., Nojiri, K., Omata, M. and Makuuchi, M. (2006), Selection of liver-transplant candidates for adult-to-adult living donor liver transplantation as the only surgical option for end-stage liver disease. Liver Transpl, 12: 1077–1083. doi: 10.1002/lt.20759
Accepted for presentation in part at the 56th Annual Meeting of the American Association for the Study of Liver Diseases.
- Issue published online: 23 JUN 2006
- Article first published online: 5 APR 2006
- Manuscript Accepted: 2 FEB 2006
- Manuscript Received: 30 OCT 2005
- Scientific Research, Ministry of Education, Culture, Sports, Science and Technology, Japan
- Research on HIV/AIDS
- Research on Measures for Intractable Diseases, Ministry of Health, Labor and Welfare, Japan
The selection of living donor liver transplantation (LDLT) recipients in regions where deceased donor liver transplantation (DDLT) is rarely performed might be different from that in other centers at which LDLT is an alternative option to DDLT. Records of adult (age ≥ 18 yr) patients referred to our center were reviewed to analyze the selection process of LDLT candidates. Among the 533 LDLT candidates, 165 (31%) were rejected due to recipient issues. Advanced hepatocellular carcinoma (HCC) was the most common reason for rejection (n = 55). Among the remaining recipients, 120 patients (22%) were rejected due to donor issues. LDLT was eventually performed in 249 (47%) of the evaluated recipients. There are few options for candidates who are unable to find live donors in regions where DDLT is unrealistic. A more effective and precise approach to recipient and donor evaluation should be pursued. Liver Transpl 12:1077–1083, 2006. © 2006 AASLD.