Twenty years of follow-up of aortohepatic conduits in liver transplantation

Authors

  • Dmitriy Nikitin,

    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Linda W. Jennings,

    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Tariq Khan,

    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Edmund Q. Sanchez,

    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Srinath Chinnakotla,

    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Henry B. Randall,

    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Greg J. McKenna,

    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Robert M. Goldstein,

    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Marlon F. Levy,

    1. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
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  • Goran B. Klintmalm

    Corresponding author
    1. Transplant Services Dallas, Baylor University Medical Center, Dallas, TX
    2. Transplant Services, Baylor All Saints Medical Center, Fort Worth, TX
    • Baylor University Medical Center, 3500 Gaston Avenue, Dallas, TX 75246
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    • Telephone: 214-820-2050; FAX: 214-820-4527


  • See Editorial on Page 1412

Abstract

Arterial problems remain a formidable challenge in liver transplantation. In many situations, an aortohepatic conduit can provide a solution. No long-term results (over 5 years) have been reported. This study was designed to assess the impact of aortohepatic conduits on graft survival after liver transplantation and the safety of aortohepatic conduits and to establish the long-term results (up to 20 years) of aortohepatic conduits. Data from 2346 adult liver transplants were prospectively collected into the computerized database and analyzed. In the majority of cases, arterial conduits were constructed from the donor iliac artery obtained at the liver retrieval. Aortohepatic conduits were required in 149 (6.4%) first transplants. The long-term graft survival after liver transplantation using aortohepatic conduits was excellent and comparable to that of the control group. The graft survival was 59% with the conduit versus 67% without the conduit at 5 years of follow-up, 50% versus 52% at 10 years, and 33% versus 35% at 15 years. With up to 20 years of follow-up, there was no statistically significant difference in graft survival, patient survival, hepatic artery complications, or biliary complications. For the same time period, there was no statistically significant difference in graft survival or patient survival for the retransplants with and without aortohepatic conduits. In conclusion, in experienced hands, aortohepatic conduits can be used safely for liver transplantation with no negative impact on long-term graft survival, patient survival, hepatic artery complications, or biliary complications. Excellent long-term results can be obtained. Liver Transpl 14:1486–1490, 2008. © 2008 AASLD.

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