Etiology and prognosis of acute liver failure in children
- 1The etiology of acute liver failure in children differs from that in adults, with metabolic conditions being commoner in Europe and North America and hepatitis A being the commonest cause in Asia and South America.
- 2Encephalopathy usually is a late feature and is not essential for the diagnosis.
- 3Unlike adults, there are no good prognostic criteria that can predict survival without liver transplantation.
- 4It is important to exclude genetic multisystem disorders before liver transplantation is considered.