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Hot-topic debate on kidney function: Renal-sparing approaches are ineffective†
Article first published online: 26 OCT 2011
Copyright © 2011 American Association for the Study of Liver Diseases
Supplement: Liver Transplant Immunosuppression: “Does One Size Fit All?”
Volume 17, Issue Supplement S3, pages S50–S53, November 2011
How to Cite
Lake, J. R. (2011), Hot-topic debate on kidney function: Renal-sparing approaches are ineffective. Liver Transpl, 17: S50–S53. doi: 10.1002/lt.22429
Potential conflict of interest: Nothing to report.
- Issue published online: 26 OCT 2011
- Article first published online: 26 OCT 2011
- Accepted manuscript online: 24 AUG 2011 01:55PM EST
- Manuscript Received: 19 AUG 2011
- Manuscript Accepted: 19 AUG 2011
1. Both acute kidney injury and chronic renal disease are common in patients undergoing liver transplantation. The etiologies are mixed.
2. The incidence of chronic renal failure after liver transplantation is unacceptable, and it has a significant impact on long-term outcomes after liver transplantation.
3. The role of calcineurin inhibitors (CNIs) in the development of posttransplant chronic renal failure is likely overrated.
4. The use of CNIs in the early posttransplant period is currently essential.
5. Whether new agents will be able to provide effective immunosuppression as primary immunosuppressives remains to be proven. Liver Transpl, 2011. © 2011 AASLD.