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Original Article

Preserving the morphology and evaluating the quality of liver grafts by hypothermic machine perfusion: A proof-of-concept study using discarded human livers†‡

  1. Diethard Monbaliu1,§,¶,*,
  2. Qiang Liu1,§,
  3. Louis Libbrecht4,
  4. Rita De Vos2,
  5. Katrien Vekemans5,
  6. Charlotte Debbaut6,
  7. Olivier Detry7,
  8. Tania Roskams2,
  9. Jos van Pelt3,
  10. Jacques Pirenne1

Article first published online: 7 DEC 2012

DOI: 10.1002/lt.23550

Issue

Liver Transplantation

Liver Transplantation

Volume 18, Issue 12, pages 1495–1507, December 2012

Additional Information

How to Cite

Monbaliu, D., Liu, Q., Libbrecht, L., De Vos, R., Vekemans, K., Debbaut, C., Detry, O., Roskams, T., van Pelt, J. and Pirenne, J. (2012), Preserving the morphology and evaluating the quality of liver grafts by hypothermic machine perfusion: A proof-of-concept study using discarded human livers. Liver Transpl, 18: 1495–1507. doi: 10.1002/lt.23550

Author Information

  1. 1

    Laboratory of Abdominal Transplant Surgery, Catholic University of Leuven, Leuven, Belgium

  2. 2

    Department of Pathology, Catholic University of Leuven, Leuven, Belgium

  3. 3

    Liver Research Facility/Hepatology Laboratory, Catholic University of Leuven, Leuven, Belgium

  4. 4

    Department of Pathology, Ghent University Hospital, Ghent, Belgium

  5. 5

    Department of Health and Technology, Leuven University College, Leuven, Belgium

  6. 6

    Biofluid, Tissue, and Solid Mechanics for Medical Applications, Institute of Biomedical Technology, Ghent University, Ghent, Belgium

  7. 7

    Department of Surgery and Transplantation, University Hospital of Liège, Liège, Belgium

  1. §

    These authors contributed equally to this work.

  2. Telephone: +32 16 348727; FAX: +32 16 348743

*Laboratory of Abdominal Transplant Surgery, Catholic University of Leuven, Herestraat 49, B-3000 Leuven, Belgium

  1. †

    Diethard Monbaliu and Jacques Pirenne are holders of a chair abdominal transplant surgery from the Centrale Afdeling voor Fractionering (Vilvoorde, Belgium).

  2. ‡

    This research was financially supported by grant IWT 040350 from the Institute for the Promotion of Innovation by Science and Technology in Flanders and by unrestricted educational grants from Roche and Astellas (Belgium).

  3. §

    These authors contributed equally to this work.

  4. Telephone: +32 16 348727; FAX: +32 16 348743

Publication History

  1. Issue published online: 7 DEC 2012
  2. Article first published online: 7 DEC 2012
  3. Accepted manuscript online: 17 SEP 2012 04:11AM EST
  4. Manuscript Accepted: 3 SEP 2012
  5. Manuscript Received: 15 NOV 2011

Funded by

  • Institute for the Promotion of Innovation by Science and Technology in Flanders. Grant Number: IWT 040350
  • Roche and Astellas (Belgium)

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