Reducing the thickness of left lateral segment grafts in neonatal living donor liver transplantation


  • This work was supported in part by grants from the Scientific Research Fund of the Japanese Ministry of Education; by a Research Grant for Immunology, Allergy, and Organ Transplant from the Japanese Ministry of Health, Labor, and Welfare (21591403, 21-04, and 21-042); and by the Foundation for Growth Science (Japan).

Address reprint requests to Mureo Kasahara, M.D., Ph.D., Organ Transplant Center, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, Japan 157-8535. Telephone: +81-3-3416-0181; FAX: +81-3-3416-2222; E-mail:


Liver transplantation is now an established treatment for children with end-stage liver disease. Left lateral segment (LLS) grafts are most commonly used in split and living donor liver transplantation in children. In very small children, LLS grafts can be too large, and further nonanatomical reduction has recently been introduced to mitigate the problem of large-for-size grafts. However, the implantation of LLS grafts can be a problem in infants and very small children because of the thickness of the grafts, and these techniques do not address problems related to thickness. We herein describe a technique for reducing the thickness of living donor left lateral grafts and successful transplantation in a 2.8-kg infant with acute liver failure. Liver Transpl 19:226–228, 2013. © 2012 AASLD.